Interferoning with Plasmodium development in the liver
- Author(s)
- Boddey, JA; Frischknecht, F;
- Details
- Publication Year 2025-04-09,Volume 33,Issue #4,Page 459-461
- Journal Title
- Cell Host & Microbe
- Abstract
- Plasmodium liver infection is limited by type I interferons (IFN-I) but the mechanisms remain unknown. In this issue of Cell Host & Microbe, Marques-da-Silva et al. reveal two IFN-I-induced pathways that trigger the fusion of lysosomes with, and the disruption of, the membranes surrounding the parasites, leading to their clearance.
- Publisher
- Cell Press
- Keywords
- *Liver/parasitology/immunology; Animals; *Plasmodium/immunology/growth & development; Humans; *Malaria/immunology/parasitology; *Interferon Type I/immunology; Lysosomes/metabolism
- Research Division(s)
- Infection and Global Health
- PubMed ID
- 40209672
- Publisher's Version
- https://doi.org/10.1016/j.chom.2025.03.007
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2026-03-16 01:38:30
Last Modified: 2026-03-16 01:52:35