ClinGen API platform for classification of human genetic variants
- Author(s)
- Shah, N; Farris, T; Zuniga, AA; Jackson, AR; Arce, J; Riehle, K; Preston, CG; Mandell, ME; Wulf, B; Cheung, G; Yu, K; Ritter, DI; Jevtic, D; Milinkov, M; Martinovic, N; Vucinic, N; Mihajlovic, A; Rubin, AF; Cline, MS; Distefano, M; Griffith, M; Griffith, OL; Wright, MW; Klein, TE; Plon, SE; Milosavljevic, A;
- Details
- Publication Year 2026-04-08,Volume 6,Issue #4,Page 101211
- Journal Title
- Cell Genomics
- Abstract
- In this commentary, we describe how the Clinical Genome Resource's (ClinGen's) application programming interface-based microservices accelerate growth and dissemination of knowledge about human genetic variation. By exposing findable, accessible, interoperable, reusable, and AI-ready variant data, ClinGen lays a foundation for next-generation software applications, AI systems, and variant classification workflows.
- Publisher
- Cell Press
- Keywords
- Humans; *Genetic Variation/genetics; *Software; *Genome, Human/genetics; Databases, Genetic; Genomics/methods
- Research Division(s)
- Bioinformatics and Computational Biology
- PubMed ID
- 41956073
- Publisher's Version
- https://doi.org/10.1016/j.xgen.2026.101211
- Open Access at Publisher's Site
https://doi.org/10.1016/j.xgen.2026.101211- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2026-04-27 03:52:46
Last Modified: 2026-04-27 03:52:54