Liquid Biopsy in Biliary Tract Cancer: When Tissue Is Not Enough
- Details
- Publication Year 2026-10-01,Volume 32,Issue #19,Page 4221-4223
- Abstract
- Circulating tumor DNA (ctDNA) profiling detects actionable genomic alterations in advanced biliary tract cancer faster (8 vs. 27 days) and more often (90% vs. 50%) than tissue, with high concordance. A recent retrospective study establishes clinical validity and a compelling access case for future prospective ctDNA-directed trials. See related article by Visa et al., p. 4374.
- Publisher
- ACCR
- Keywords
- Humans; *Biliary Tract Neoplasms/genetics/diagnosis/blood/pathology; Liquid Biopsy/methods; *Circulating Tumor DNA/blood/genetics; *Biomarkers, Tumor/genetics/blood
- Research Division(s)
- Personalised Oncology
- PubMed ID
- 42545218
- Publisher's Version
- https://doi.org/10.1158/1078-0432.Ccr-26-2090
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2026-10-02 08:18:55
Last Modified: 2026-10-02 08:19:08