The L6 membrane proteins - A new four-transmembrane superfamily
- Author(s)
- Wright, MD; Ni, J; Rudy, GB;
- Details
- Publication Year 2000-08,Volume 9,Issue #8,Page 1594-1600
- Journal Title
- PROTEIN SCIENCE
- Publication Type
- Journal Article
- Abstract
- L6, IL-TMP, and TM4SF5 are cell surface proteins predicted to have four transmembrane domains. Previous sequence analysis led to their assignment as members of the tetraspanin superfamily. In this paper, we identify a new sequence (L6D) that is strikingly similar to L6, IL-TMP, and TM4SF5. Analyses of these four sequences indicate that they are not significantly related to genuine tetraspanins, but instead constitute their own L6 superfamily.
- Publisher
- CAMBRIDGE UNIV PRESS
- Keywords
- TUMOR-ASSOCIATED ANTIGEN; MOLECULAR-CLONING; SCHISTOSOMA-MANSONI; SURFACE-ANTIGEN; CDNA; EXPRESSION; SEQUENCE; ANTIBODY; GENE; IDENTIFICATION
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- Refer to copyright notice on published article.
Creation Date: 2000-08-01 12:00:00