Mapping of human autoepitopes in type 1 diabetes
Author(s)
Honeyman, MC;
Details
Publication Year 2000-01,Volume 8,Issue #1-2,Page 30-32
Journal Title
IMMUNOLOGIST
Publication Type
Journal Article
Abstract
In type 1 diabetes,specific human leukocyte antigen (HLA) alleles confer susceptibility and are thought to present autoantigens to T cells that destroy pancreatic beta cells. Here, Margo C. Honeyman uses ct combination of experimental and computer modeling methods to predict peptides that will bind particular HLA alleles and elicit T-cell responses. This may be used to define T-cell epitopes in other diseases.
Publisher
HOGREFE & HUBER PUBLISHERS
Keywords
PEPTIDE
Terms of Use/Rights Notice
Refer to copyright notice on published article.


Creation Date: 2000-01-01 12:00:00
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