Manipulation of mucosa-mediated immunoregulation
Details
Publication Year 2000-01,Volume 8,Issue #1-2,Page 28-30
Journal Title
IMMUNOLOGIST
Publication Type
Journal Article
Abstract
Mucosal administration of antigen is known to have tolerogenic potential; however, it may also prime systemic cytotoxic T lymphocytes (CTL) and even exacerbate autoimmune disease. Here, Leonard C. Harrison and colleagues use the nonobese diabetic (NOD) mouse model of diabetes to develop strategies to minimize immunity and maximize tolerance, that have broad implications for other diseases.
Publisher
HOGREFE & HUBER PUBLISHERS
Keywords
MYELIN BASIC-PROTEIN; CD4(+) T-CELLS; NOD MICE; RESPONSES; INSULIN; SUPPRESSION; INDUCTION
Terms of Use/Rights Notice
Refer to copyright notice on published article.


Creation Date: 2000-01-01 12:00:00
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