Affinity maturation in the B-cell response to antigen
- Author(s)
- Tarlinton, D; Light, A; Smith, K; Nossal, GJV;
- Details
- Publication Year 2000-01,Volume 8,Issue #1-2,Page 9-11
- Journal Title
- IMMUNOLOGIST
- Publication Type
- Journal Article
- Abstract
- Affinity maturation of antibody forms part of immunological dogma, although its regulation is poorly understood. Here, David Tarlinton, Amanda Light, Kenneth Smith, and Gustav J.V. Nossal describe their considerable contribution to the analysis of B-cell responses to antigen, and they propose a model for the operation of the germinal center (GC) based on their dissection of various B-cell sub-populations.
- Publisher
- HOGREFE & HUBER PUBLISHERS
- Keywords
- PRIMARY IMMUNE-RESPONSE; MOLECULAR CHARACTERIZATION; GERMINAL-CENTERS; MEMORY; ANTIBODY; RECRUITMENT; NP; SINGLE
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2000-01-01 12:00:00