Affinity maturation in the B-cell response to antigen
Details
Publication Year 2000-01,Volume 8,Issue #1-2,Page 9-11
Journal Title
IMMUNOLOGIST
Publication Type
Journal Article
Abstract
Affinity maturation of antibody forms part of immunological dogma, although its regulation is poorly understood. Here, David Tarlinton, Amanda Light, Kenneth Smith, and Gustav J.V. Nossal describe their considerable contribution to the analysis of B-cell responses to antigen, and they propose a model for the operation of the germinal center (GC) based on their dissection of various B-cell sub-populations.
Publisher
HOGREFE & HUBER PUBLISHERS
Keywords
PRIMARY IMMUNE-RESPONSE; MOLECULAR CHARACTERIZATION; GERMINAL-CENTERS; MEMORY; ANTIBODY; RECRUITMENT; NP; SINGLE
Terms of Use/Rights Notice
Refer to copyright notice on published article.


Creation Date: 2000-01-01 12:00:00
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