Mice that are congenic for the char2 locus are susceptible to malaria
- Author(s)
- Burt, RA; Marshall, VM; Wagglen, J; Rodda, FR; Senyschen, D; Baldwin, TM; Buckingham, LA; Foote, SJ;
- Details
- Publication Year 2002-08,Volume 70,Issue #8,Page 4750-4753
- Journal Title
- INFECTION AND IMMUNITY
- Publication Type
- Journal Article
- Abstract
- A major advance has been made towards the positional cloning of char2 (a quantitative trait locus encoding resistance to Plasmodium chabaudi malaria). Mice congenic for the locus have been used to fine map the gene and to prove that char2 plays a significant role in the outcome of malarial infection, independently of other resistance loci.
- Publisher
- AMER SOC MICROBIOLOGY
- Keywords
- MOUSE MALARIA; PARASITEMIA; MAPS
- Publisher's Version
- https://doi.org/10.1128/IAI.70.8.4750-4753.2002
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2002-08-01 12:00:00