Encystation-specific vesicles in Giardia: a primordial Golgi or just another secretory compartment?
Author(s)
Marti, M; Hehl, AB;
Details
Publication Year 2003-10,Volume 19,Issue #10,Page 440-446
Journal Title
TRENDS IN PARASITOLOGY
Publication Type
Journal Article
Abstract
Giardia intestinalis is better known to cause diarrheal disease than to be the object of basic research in cell biology. However, this is about to change: the unique biology of this parasite and a genome project combine to earn this amitochondriate a place among the better-known model organisms. One consequence of its phylogenetic status is that Giardia has at the same time highly specialized traits, and basic features such as an apparently Golgi-less secretory system. This article discusses the unique nature of the Giardia secretory system and implications of novel insights in the context of eukaryotic endomembrane organization and evolution.
Publisher
ELSEVIER SCI LTD
Keywords
CYST WALL PROTEIN; VARIANT SURFACE PROTEIN; ENDOPLASMIC-RETICULUM; ENDOMEMBRANE SYSTEM; TRYPANOSOMA-BRUCEI; GENE-TRANSFER; LAMBLIA; APPARATUS; ORGANIZATION; EUKARYOTES
Terms of Use/Rights Notice
Refer to copyright notice on published article.


Creation Date: 2003-10-01 12:00:00
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