The role of dendritic cell subsets in immunity to viruses
- Author(s)
- Carbone, FR; Heath, WR;
- Details
- Publication Year 2003-08,Volume 15,Issue #4,Page 416-420
- Journal Title
- CURRENT OPINION IN IMMUNOLOGY
- Publication Type
- Journal Article
- Abstract
- Dendritic cells orchestrate the adaptive immune response. As well as presenting MHC-restricted antigen for T-cell activation, they provide all the co-receptor signals required for full T-cell priming. As a consequence, they play a central role in the immune response to infections caused by many pathogenic agents, including viruses. In recent times, it has become apparent that dendritic cells represent a particularly heterogeneous population with individual subsets playing specialized roles in response to infection.
- Publisher
- CURRENT BIOLOGY LTD
- Keywords
- CD8(+) T-CELLS; ANTIGEN-PRESENTING CELLS; NATURAL-KILLER-CELLS; IN-VIVO; LYMPH-NODES; CROSS-PRESENTATION; SURFACE PHENOTYPE; SELF-TOLERANCE; CUTTING EDGE; HUMAN BLOOD
- Publisher's Version
- https://doi.org/10.1016/S0952-7915(03)00074-8
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2003-08-01 12:00:00