Plasmodium falciparum homologue of the genes for Plasmodium vivax and Plasmodium yoelii adhesive proteins, which is transcribed but not translated
- Author(s)
- Taylor, HM; Triglia, T; Thompson, J; Sajid, M; Fowler, R; Wickham, ME; Cowman, AF; Holder, AA;
- Details
- Publication Year 2001-06,Volume 69,Issue #6,Page 3635-3645
- Journal Title
- INFECTION AND IMMUNITY
- Publication Type
- Journal Article
- Abstract
- The 235-kDa family of rhoptry proteins in Plasmodium yoelii and the two reticulocyte binding proteins of P. vivax comprise a family of proteins involved in host cell selection and erythrocyte invasion. Here we described a member of the gene family found in P. falciparum (PfRH3) that is transcribed in its entirety, under stage-specific control, with correct splicing of the intron, but appears not to be translated, probably due to two reading frameshifts at the 5' end of the gene.
- Publisher
- AMER SOC MICROBIOLOGY
- Keywords
- ERYTHROCYTE BINDING ANTIGEN; CHROMOSOME SIZE POLYMORPHISM; MEROZOITE SURFACE PROTEIN-1; MASS RHOPTRY PROTEIN; HOST-CELL SELECTION; DUFFY-BLOOD-GROUP; MALARIA PARASITES; RODENT MALARIA; GLYCOPHORIN-A; INVASION
- Publisher's Version
- https://doi.org/10.1128/IAI.69.6.3635-3645.2001
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2001-06-01 12:00:00