HtrA - A renaissance protein
- Details
- Publication Year 2002-06,Volume 10,Issue #6,Page 737-739
- Journal Title
- STRUCTURE
- Publication Type
- Journal Article
- Abstract
- Initially identified as proteases, members of the HtrA/DegP family of proteins have also been shown to act as chaperones in bacteria, and more recently implicated, as regulators of apoptosis in mammals. Two new structures of mammalian HtrA2 and E. coli DegP provide insights into the origin of this plurality of function.
- Publisher
- CELL PRESS
- Keywords
- SERINE-PROTEASE; CELL-DEATH; APOPTOSIS; INHIBITOR; XIAP; MITOCHONDRIA; OMI/HTRA2; INTERACTS; CHAPERONE
- Publisher's Version
- https://doi.org/10.1016/S0969-2126(02)00782-7
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2002-06-01 12:00:00