Immune self-tolerance mechanisms
- Author(s)
- Miller, JFAP;
- Details
- Publication Year 2001-10-27,Volume 72,Issue #8,Page S5-S9
- Journal Title
- TRANSPLANTATION
- Publication Type
- Journal Article
- Abstract
- Tolerance of both T and B cells to self-antigens can be achieved through a great variety of different routes, at the level of the primary lymphoid organs (thymus and bone marrow) and throughout the secondary lymphoid tissues. Whether self-reactive lymphocytes ignore their target autoantigen, or are tolerized by the various mechanisms discussed, depends on the circumstances.
- Publisher
- LIPPINCOTT WILLIAMS & WILKINS
- Keywords
- T-CELLS; TISSUE ANTIGENS; LYMPHOCYTE; AUTOIMMUNITY; RECOGNITION; REPERTOIRE; APOPTOSIS; PATHWAYS; THYMUS; DANGER
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2001-10-27 12:00:00