THE HEMATOPOIETIC REGULATORS - AN EMBARRASSMENT OF RICHES
- Author(s)
- Metcalf, D;
- Details
- Publication Year 1992-12,Volume 14,Issue #12,Page 799-805
- Journal Title
- BIOESSAYS
- Publication Type
- Journal Article
- Abstract
- A large, and growing, group of glycoprotein regulators is now recognized to control the proliferation, maturation and functional activity of the eight major families of blood cells. Each hemopoietic regulator is the product of multiple cell types and there is a puzzling redundancy of regulators able to stimulate each subfamily of hemopoietic cells. Each regulator is polyfunctional but it remains unclear how a single type of activated receptor is able to initiate the diverse cellular responses induced.
- Publisher
- COMPANY OF BIOLOGISTS LTD
- Keywords
- COLONY-STIMULATING FACTOR; FACTOR-I CSF-1; MURINE GM-CSF; GRANULOCYTE-COLONY; HEMATOPOIETIC-CELLS; RECEPTOR GENES; MULTI-CSF; GROWTH; MICE; ERYTHROPOIETIN
- Publisher's Version
- https://doi.org/10.1002/bies.950141202
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 1992-12-01 12:00:00