CONTROL OF GRANULOCYTES AND MACROPHAGES - MOLECULAR, CELLULAR, AND CLINICAL ASPECTS
- Author(s)
- Metcalf, D;
- Details
- Publication Year 1991-10-25,Volume 254,Issue #5031,Page 529-533
- Journal Title
- SCIENCE
- Publication Type
- Journal Article
- Abstract
- The production and functional activity of two important white blood cells, the granulocytes and macrophages, are regulated mainly by a group of glycoprotein colony-stimulating factors. The colony-stimulating factors have been mass-produced with recombinant technology and are now proving of value in preventing or suppressing infections in a variety of individuals with subnormal or defective formation of blood cells.
- Publisher
- AMER ASSOC ADVANCEMENT SCIENCE
- Keywords
- COLONY-STIMULATING FACTOR; GM-CSF; PHASE-I/II; MULTI-CSF; GROWTH-FACTORS; CELLS; RECEPTORS; MICE; HEMATOPOIESIS; DIFFERENTIATION
- Publisher's Version
- https://doi.org/10.1126/science.1948028
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 1991-10-25 12:00:00