TRANSGENIC MICE AS IMMUNE-SYSTEM MODELS
- Author(s)
- Morahan, G;
- Details
- Publication Year 1991-04,Volume 3,Issue #2,Page 219-223
- Journal Title
- CURRENT OPINION IN IMMUNOLOGY
- Publication Type
- Journal Article
- Abstract
- In the past year, transgenic mice have continued to be powerful models for the investigation of various features of the immune system, particularly for studies of lymphocyte differentiation and tolerance. Major achievements have included the definition of intra-thymic selection events in T-cell differentiation, and the demonstration of extra-thymic tolerance resulting from clonal anergy.
- Publisher
- CURRENT BIOLOGY LTD
- Keywords
- DEPENDENT DIABETES-MELLITUS; PANCREATIC BETA-CELLS; DELTA-T-CELLS; CLASS-II MHC; SELF-TOLERANCE; CLONAL-DELETION; EXPRESSION; GAMMA; MOLECULES; ANTIBODY
- Publisher's Version
- https://doi.org/10.1016/0952-7915(91)90054-5
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 1991-04-01 12:00:00