PLASMODIUM-FALCIPARUM RING-INFECTED ERYTHROCYTE SURFACE-ANTIGEN IS RELEASED FROM MEROZOITE DENSE GRANULES AFTER ERYTHROCYTE INVASION
Details
Publication Year 1991-03, Volume 59, Issue #3, Page 1183-1187
Journal Title
INFECTION AND IMMUNITY
Publication Type
Journal Article
Abstract
Electron microscopy was used to study the fate of Plasmodium falciparum ring-infected erythrocyte surface antigen after merozoite invasion by using postembedding immunolabeling. The antigen was localized to small dense granules located centrally or laterally in free merozoites. In newly invaded erythrocytes, labeling was found in pockets of the parasitophorous vacuole space or in aggregates closely associated with the parasitophorous vacuole. These patterns indicate that ring-infected erythrocyte surface antigen is contained in merozoite dense granules that are released after merozoite invasion and not via apical rhoptry ducts at the time of merozoite attachment.
Publisher
AMER SOC MICROBIOLOGY
Keywords
PARASITOPHOROUS VACUOLE; KNOWLESI MEROZOITES; HUMAN-ANTIBODIES; ASEXUAL STAGES; MEMBRANE; PARASITE; MALARIA; LOCALIZATION; MOVEMENT; RESA
Rights Notice
Refer to copyright notice on published article.


Creation Date: 1991-03-01 12:00:00
Last Modified: 0001-01-01 12:00:00
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