INTERLEUKIN-1, IMMUNE ACTIVATION PATHWAYS, AND DIFFERENT MECHANISMS IN OSTEOARTHRITIS AND RHEUMATOID-ARTHRITIS
- Author(s)
- KIRKHAM, B;
- Details
- Publication Year 1991-06,Volume 50,Issue #6,Page 395-400
- Journal Title
- ANNALS OF THE RHEUMATIC DISEASES
- Publication Type
- Journal Article
- Abstract
- Interleukin-1 seems to be important in the immunopathology of many forms of arthritis, and this has been increasingly recognised in the last few years. Its production is complicated and various inhibitors have been described. It is widely distributed, forming part of the network of cytokines, and seems to behave differently in osteoarthritis and rheumatoid arthritis. Perhaps these differences can be exploited.
- Publisher
- BRITISH MED JOURNAL PUBL GROUP
- Keywords
- TUMOR NECROSIS FACTOR; HUMAN ARTICULAR CHONDROCYTES; PERIPHERAL-BLOOD MONOCYTES; COLONY-STIMULATING FACTOR; ANTIGEN-INDUCED ARTHRITIS; HUMAN SYNOVIAL-CELLS; OSTEO-ARTHRITIS; GROWTH-FACTOR; FACTOR-ALPHA; U937 CELLS
- Publisher's Version
- https://doi.org/10.1136/ard.50.6.395
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 1991-06-01 12:00:00