musculin: a murine basic helix-loop-helix transcription factor gene expressed in embryonic skeletal muscle
- Author(s)
- Robb, L; Hartley, L; Wang, CC; Harvey, RP; Begley, CG;
- Details
- Publication Year 1998-08,Volume 76,Issue #1-2,Page 197-201
- Journal Title
- MECHANISMS OF DEVELOPMENT
- Publication Type
- Journal Article
- Abstract
- We describe the embryonic expression of musclin, a new murine member of the bHLH family of transcription factors. Musculin protein is closely related to human ABF-1. which is expressed in activated B cells, and to epicardin/capsulin/Pod-1, which is expressed in branchial myoblasts. visceral and urogenital mesoderm and epicardium. In situ hyhridisation revealed musculin expression in embryos was largely restricted to the embryonic skeletal muscle lineage. While all skeletal muscles expressed the gene, only a subset of myocytes within each muscle were positive, indicating molecular heterogeneity within fetal muscle. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.
- Publisher
- ELSEVIER SCIENCE BV
- Keywords
- DEVELOPING NERVOUS-SYSTEM; PARAXIAL MESODERM; BHLH PROTEINS; MYOGENESIS; EMBRYOGENESIS
- Publisher's Version
- https://doi.org/10.1016/S0925-4773(98)00122-1
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 1998-08-01 12:00:00