Cross-presentation: A general mechanism for CTL immunity and tolerance
- Author(s)
- Carbone, FR; Kurts, C; Bennett, SRM; Miller, JFAP; Heath, WR;
- Details
- Publication Year 1998-08,Volume 19,Issue #8,Page 368-373
- Journal Title
- IMMUNOLOGY TODAY
- Publication Type
- Journal Article
- Abstract
- MHC class I-restricted presentation is usually associated with the processing of endogenous antigens. However, this restriction element can present antigens that do not originate within the presenting cells. Here, Francis Carbone and colleagues describe how such cross-presentation is critical for cytotoxic T-cell surveillance of peripheral antigens, both self and foreign, located outside the secondary lymphoid compartment.
- Publisher
- ELSEVIER SCI LTD
- Keywords
- MAJOR HISTOCOMPATIBILITY COMPLEX; TOXIC LYMPHOCYTES-T; CLASS-I; CD28-B7 INTERACTIONS; CYTOLYTIC RESPONSE; VIRUS-INFECTION; VIRAL-PROTEINS; CELLS; ANTIGEN; MACROPHAGES
- Publisher's Version
- https://doi.org/10.1016/S0167-5699(98)01301-2
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 1998-08-01 12:00:00