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Showing results for: AUTHOR - Adams, JM

Found: 216 results

Robust autoactivation for apoptosis by BAK but not BAX highlights BAK as an important therapeutic target Cell Death & Disease - 2020-04-23 Iyer, S; Uren, RT; Dengler, MA; Shi, MX; Uno, E; Adams, JM; Dewson, G; Kluck, RM
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Potent efficacy of MCL-1 inhibitor-based therapies in preclinical models of mantle cell lymphoma Oncogene - 2020-02 Dengler, MA; Teh, CE; Thijssen, R; Gangoda, L; Lan, P; Herold, MJ; Gray, DH; Kelly, GL; Roberts, AW; Adams, JM
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BAX and BAK become killers without a BH3 trigger Cell Research - 2019-11-15 Adams, JM
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BAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial Association Cell Reports - 2019-04-09 Dengler, MA; Robin, AY; Gibson, L; Li, MX; Sandow, JJ; Iyer, S; Webb, AI; Westphal, D; Dewson, G; Adams, JM
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By reducing global mRNA translation in several ways, 2-deoxyglucose lowers MCL-1 protein and sensitizes hemopoietic tumor cells to BH3 mimetic ABT737 Cell Death and Differentiation - 2018-12-11 Tailler, M; Lindqvist, LM; Gibson, L; Adams, JM
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The BCL-2 arbiters of apoptosis and their growing role as cancer targets Cell Death and Differentiation - 2018-01 Adams, JM; Cory, S
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Critical B-lymphoid cell intrinsic role of endogenous MCL-1 in c-MYC-induced lymphomagenesis Cell Death Dis - 2016 Grabow, S; Kelly, GL; Delbridge, AR; Kelly, PN; Bouillet, P; Adams, JM; Strasser, A
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Functional antagonism between pro-apoptotic BIM and anti-apoptotic BCL-XL in MYC-induced lymphomagenesis. Oncogene - 2015-04 Delbridge, AR; Grabow, S; Bouillet, P; Adams, JM; Strasser, A
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Donald Metcalf: The father of modern hematology Proceedings of the National Academy of Sciences of the United States of America - 2015-03-03 Adams, JM; Cory, S
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NMR studies of interactions between Bax and BH3 domain-containing peptides in the absence and presence of CHAPS Archives of biochemistry and biophysics - 2014-11-19 Yao, S; Westphal, D; Babon, JJ; Thompson, GV; Robin, AY; Adams, JM; Colman, PM; Czabotar, PE
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Apoptotic pore formation is associated with in-plane insertion of Bak or Bax central helices into the mitochondrial outer membrane Proceedings of the National Academy of Sciences of the United States of America - 2014-09-16 Westphal, D; Dewson, G; Menard, M; Frederick, P; Iyer, S; Bartolo, R; Gibson, L; Czabotar, PE; Smith, BJ; Adams, JM; Kluck, RM
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Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy Nature Reviews Molecular Cell Biology - 2014-01 Czabotar, PE; Lessene, G; Strasser, A; Adams, JM
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THE ROLE OF THE BCL-2 PROTEIN FAMILY TN TUMORIGENESIS AND CANCER THERAPY EXPERIMENTAL HEMATOLOGY - 2013-08 Strasser, A; Kelly, G; Glaser, S; Kelly, PN; Grabow, S; Delbridge, A; Herold, M; Adams, JM
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Discovery of Potent and Selective Benzothiazole Hydrazone Inhibitors of Bcl-XL. Journal of Medicinal Chemistry - 2013-07-11 Sleebs, BE; Kersten, WJ; Kulasegaram, S; Nikolakopoulos, G; Hatzis, E; Moss, RM; Parisot, JP; Yang, H; Czabotar, PE; Fairlie, WD; Lee, EF; Adams, JM; Chen, L; van Delft, MF; Lowes, KN; Wei, A; Huang, DC; Colman, PM; Street, IP; Baell, JB; Watson, K; Lessene, G
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Structure-guided design of a selective BCL-X-L inhibitor NATURE CHEMICAL BIOLOGY - 2013-06 Lessene, G; Czabotar, PE; Sleebs, BE; Zobel, K; Lowes, KN; Adams, JM; Baell, JB; Colman, PM; Deshayes, K; Fairbrother, WJ; Flygare, JA; Gibbons, P; Kersten, WJA; Kulasegaram, S; Moss, RM; Parisot, JP; Smith, BJ; Street, IP; Yang, H; Huang, DCS; Watson, KG
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Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis CELL - 2013-01-31 Czabotar, PE; Westphal, D; Dewson, G; Ma, S; Hockings, C; Fairlie, WD; Lee, EF; Yao, SG; Robin, AY; Smith, BJ; Huang, DCS; Kluck, RM; Adams, JM; Colman, PM
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Prophylactic treatment with the BH3 mimetic ABT-737 impedes Myc-driven lymphomagenesis in mice CELL DEATH AND DIFFERENTIATION - 2013-01 Kelly, PN; Grabow, S; Delbridge, ARD; Adams, JM; Strasser, A
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Therapeutic potential of a peptide targeting BCL-2 cell guardians in cancer JOURNAL OF CLINICAL INVESTIGATION - 2012-06 Adams, JM
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Endogenous Bcl-x(L) is essential for Myc-driven lymphomagenesis in mice BLOOD - 2011-12-08 Kelly, PN; Grabow, S; Delbridge, ARD; Strasser, A; Adams, JM
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Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases EMBO JOURNAL - 2011-09-14 Strasser, A; Cory, S; Adams, JM
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Destruction of tumor vasculature and abated tumor growth upon VEGF blockade is driven by proapoptotic protein Bim in endothelial cells JOURNAL OF EXPERIMENTAL MEDICINE - 2011-07-04 Naik, E; O'Reilly, LA; Asselin-Labat, ML; Merino, D; Lin, A; Cook, M; Coultas, L; Bouillet, P; Adams, JM; Strasser, A
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Individual and overlapping roles of BH3-only proteins Bim and Bad in apoptosis of lymphocytes and platelets and in suppression of thymic lymphoma development CELL DEATH AND DIFFERENTIATION - 2010-10 Kelly, PN; White, MJ; Goschnick, MW; Fairfax, KA; Tarlinton, DM; Kinkel, SA; Bouillet, P; Adams, JM; Kile, BT; Strasser, A
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Apoptosis-promoted tumorigenesis: gamma-irradiation-induced thymic lymphomagenesis requires Puma-driven leukocyte death GENES & DEVELOPMENT - 2010-08-01 Michalak, EM; Vandenberg, CJ; Delbridge, ARD; Wu, L; Scott, CL; Adams, JM; Strasser, A
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Apoptosis and non-inflammatory phagocytosis can be induced by mitochondrial damage without caspases CELL DEATH AND DIFFERENTIATION - 2010-05 van Delft, MF; Smith, DP; Lahoud, MH; Huang, DCS; Adams, JM
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Bak Activation for Apoptosis Involves Oligomerization of Dimers via Their alpha 6 Helices MOLECULAR CELL - 2009-11-25 Dewson, G; Kratina, T; Czabotar, P; Day, CL; Adams, JM; Kluck, RM
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