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Showing results for: AUTHOR - Chang, C
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BCL-XL inhibition by BH3-mimetic drugs induces apoptosis in models of Epstein-Barr virus-associated T/NK-cell lymphoma
Blood Advances - 2020-10-13
Sejic, N; George, LC; Tierney, RJ; Chang, C; Kondrashova, O; MacKinnon, RN; Lan, P; Bell, AI; Lessene, G; Long, HM; Strasser, A; Shannon-Lowe, C; Kelly, GL
Link to Open Access at Publisher's Site
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BCL-W is dispensable for the sustained survival of select Burkitt lymphoma and diffuse large B-cell lymphoma cell lines
Blood Advances - 2020-01-28
Diepstraten, ST; Chang, C; Tai, L; Gong, JN; Lan, P; Dowell, AC; Taylor, GS; Strasser, A; Kelly, GL
Link to Open Access at Publisher's Site
EBV BCL-2 homologue BHRF1 drives chemoresistance and lymphomagenesis by inhibiting multiple cellular pro-apoptotic proteins
Cell Death and Differentiation - 2019-10-23
Fitzsimmons, L; Cartlidge, R; Chang, C; Sejic, N; Galbraith, LCA; Suraweera, CD; Croom-Carter, D; Dewson, G; Tierney, RJ; Bell, AI; Shannon-Lowe, C; Herold, MJ; Rickinson, AB; Colman, PM; Huang, DCS; Strasser, A; Kvansakul, M; Rowe, M; Kelly, GL
Link to Publisher's Version
VDAC2 enables BAX to mediate apoptosis and limit tumor development
Nature Communications - 2018-11-26
Chin, HS; Li, MX; Tan, IKL; Ninnis, RL; Reljic, B; Scicluna, K; Dagley, LF; Sandow, JJ; Kelly, GL; Samson, AL; Chappaz, S; Khaw, SL; Chang, C; Morokoff, A; Brinkmann, K; Webb, A; Hockings, C; Hall, CM; Kueh, AJ; Ryan, MT; Kluck, RM; Bouillet, P; Herold, MJ; Gray, DHD; Huang, DCS; van Delft, MF; Dewson, G
Link to Open Access at Publisher's Site
Mutant TRP53 exerts a target gene-selective dominant-negative effect to drive tumor development
Genes & Development - 2018-11-01
Aubrey, BJ; Janic, A; Chen, Y; Chang, C; Lieschke, EC; Diepstraten, ST; Kueh, AJ; Bernardini, JP; Dewson, G; O'Reilly, LA; Whitehead, L; Voss, AK; Smyth, GK; Strasser, A; Kelly, GL
Link to Publisher's Version
Humanized Mcl-1 mice enable accurate pre-clinical evaluation of MCL-1 inhibitors destined for clinical use
Blood - 2018-10
Brennan, MS; Chang, C; Tai, L; Lessene, G; Strasser, A; Dewson, G; Kelly, GL; Herold, MJ
Link to Publisher's Version
Coordinated repression of BIM and PUMA by Epstein-Barr virus latent genes maintains the survival of Burkitt lymphoma cells
Cell Death and Differentiation - 2017-09-29
Fitzsimmons, L; Boyce, AJ; Wei, W; Chang, C; Croom-Carter, D; Tierney, RJ; Herold, MJ; Bell, AI; Strasser, A; Kelly, GL; Rowe, M
Link to Open Access at Publisher's Site
ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress
DNA Repair - 2017-06-17
Liu, R; KING, A; Hoch, NC; Chang, C; Kelly, GL; Deans, AJ; Heierhorst, J
Link to Open Access at Publisher's Site
The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models
Nature - 2016-10-19
Kotschy, A; Szlavik, Z; Murray, J; Davidson, J; Maragno, AL; Le Toumelin-Braizat, G; Chanrion, M; Kelly, GL; Gong, JN; Moujalled, DM; Bruno, A; Csekei, M; Paczal, A; Szabo, ZB; Sipos, S; Radics, G; Proszenyak, A; Balint, B; Ondi, L; Blasko, G; Robertson, A; Surgenor, A; Dokurno, P; Chen, I; Matassova, N; Smith, J; Pedder, C; Graham, C; Studeny, A; Lysiak-Auvity, G; Girard, AM; Grave, F; Segal, D; Riffkin, CD; Pomilio, G; Galbraith, LC; Aubrey, BJ; Brennan, MS; Herold, MJ; Chang, C; Guasconi, G; Cauquil, N; Melchiore, F; Guigal-Stephan, N; Lockhart, B; Colland, F; Hickman, JA; Roberts, AW; Huang, DC; Wei, AH; Strasser, A; Lessene, G; Geneste, O
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MCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL
Cell Death Dis - 2016
Vikstrom, IB; Slomp, A; Carrington, EM; Moesbergen, LM; Chang, C; Kelly, GL; Glaser, SP; Jansen, JH; Leusen, JH; Strasser, A; Huang, DC; Lew, AM; Peperzak, V; Tarlinton, DM
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