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The role of LNK (SH2B3) in the regulation of JAK-STAT signalling in haematopoiesis
Pharmaceuticals - 2022-12-24
Morris, R; Butler, L; PERKINS, A; Kershaw, NJ; Babon, JJ
Abstract
Non-genetic determinants of malignant clonal fitness at single-cell resolution
Nature - 2022-12-08
Fennell, KA; Vassiliadis, D; Lam, EYN; Martelotto, LG; Balic, JJ; Hollizeck, S; Weber, TS; Semple, T; Wang, Q; Miles, DC; MacPherson, L; Chan, YC; Guirguis, AA; Kats, LM; Wong, ES; Dawson, SJ; Naik, SH; Dawson, MA
Abstract
Identifying targets of protective antibodies against severe malaria in Papua, Indonesia using locally expressed domains of Plasmodium falciparum Erythrocyte Membrane Protein 1
Infection and Immunity - 2022-12-06
Rambhatla, JS; Tonkin-Hill, GQ; Takashima, E; Tsuboi, T; Noviyanti, R; Trianty, L; Sebayang, BF; Lampah, DA; Marfurt, J; Price, RN; Anstey, NM; Papenfuss, AT; Damelang, T; Chung, AW; Duffy, MF; Rogerson, SJ
Abstract
Cell death in skin function, inflammation, and disease
Biochemical Journal - 2022-08-12
Anderton, H; Alqudah, S
Abstract
Neonatal BCG vaccination is associated with a long-term DNA methylation signature in circulating monocytes
Science Advances - 2022-08-05
Bannister, S; Kim, B; Domínguez-Andrés, J; Kilic, G; Ansell, BRE; Neeland, MR; Moorlag, Sjcfm; Matzaraki, V; Vlahos, A; Shepherd, R; Germano, S; Bahlo, M; Messina, NL; Saffery, R; Netea, MG; Curtis, N; Novakovic, B
Abstract
Inhibition of LSD1 with bomedemstat sensitizes small cell lung cancer to immune checkpoint blockade and T cell killing
Clinical Cancer Research - 2022-08-03
Hiatt, JB; Sandborg, H; Garrison, SM; Arnold, HU; Liao, SY; Norton, JP; Friesen, TJ; Wu, F; Sutherland, KD; Rienhoff, HY; Martins, R; Houghton, AM; Srivastava, S; MacPherson, D
Abstract
Impaired physical function in patients with idiopathic inflammatory myopathies: results from the multicentre COVAD patient-reported e-survey
Rheumatology - 2022-08-03
Yoshida, A; Kim, M; Kuwana, M; Naveen, R; Makol, A; Sen, P; Lilleker, JB; Agarwal, V; Kardes, S; Day, J; Milchert, M; Joshi, M; Gheita, T; Salim, B; Velikova, T; Edgar Gracia-Ramos, A; Parodis, I; O'Callaghan, AS; Nikiphorou, E; Chatterjee, T; Tan, AL; Nune, A; Cavagna, L; Saavedra, MA; Shinjo, SK; Ziade, N; Knitza, J; Distler, O; Chinoy, H; Agarwal, V; Aggarwal, R; Gupta, L
Abstract
VERONICA: Randomized phase II study of fulvestrant and venetoclax in ER-positive metastatic breast cancer post-CDK4/6 inhibitors - efficacy, safety, and biomarker results
Clinical Cancer Research - 2022-08-02
Lindeman, GJ; Fernando, TM; Bowen, R; Jerzak, KJ; Song, X; DECKER, T; Boyle, F; McCune, S; Armstrong, A; Shannon, C; Bertelli, G; Chang, CW; Desai, R; Gupta, K; Wilson, TR; Flechais, A; Bardia, A
Abstract
Corrigendum to 'A transcriptomic dataset evaluating the effect of radiotherapy injury on cells of skin and soft tissue' Data in Brief 41 (2022) 107828
Data in Brief - 2022-08
Shuka, L; Lee, SA; Du, MRM; Karnezis, T; Ritchie, ME; Shayan, R
Abstract
Utility of SARS-CoV-2 rapid antigen testing for patient triage in the emergency department: A clinical implementation study in Melbourne, Australia
Lancet Regional Health Western Pacific - 2022-08
Bond, KA; Smith, B; Gardiner, E; Liew, KC; Williams, E; Walsham, N; Putland, M; Williamson, DA
Abstract
Outcomes following venetoclax-based treatment in therapy-related myeloid neoplasms
American Journal of Hematology - 2022-08
Shah, MV; Chhetri, R; Dholakia, R; Kok, CH; Gangat, N; Alkhateeb, HB; Al-Kali, A; Patnaik, MM; Baranwal, A; Greipp, PT; He, R; Begna, KH; Tiong, IS; Wei, AH; Hiwase, D
Abstract
NEK1 and STMN2 short tandem repeat lengths are not associated with Australian amyotrophic lateral sclerosis risk
Neurobiology of Aging - 2022-08
Grima, N; Henden, L; Fearnley, LG; Rowe, DB; D'Silva, S; Pamphlett, R; Adams, L; Kiernan, MC; Mazumder, S; Timmins, HC; Zoing, M; Bahlo, M; Blair, IP; Williams, KL
Abstract
Detection of repeat expansions in large next generation DNA and RNA sequencing data without alignment
Scientific Reports - 2022-07-30
Fearnley, LG; Bennett, MF; Bahlo, M
Abstract
Clinical impact of whole-genome sequencing in patients with early-onset dementia
Journal of Neurology Neurosurgery & Psychiatry - 2022-07-29
Huq, AJ; Thompson, B; Bennett, MF; Bournazos, A; Bommireddipalli, S; Gorelik, A; Schultz, J; Sexton, A; Purvis, R; West, K; Cotter, M; Valente, G; Hughes, A; Riaz, M; Walsh, M; Farrand, S; Loi, SM; Kilpatrick, T; Brodtmann, A; Darby, D; Eratne, D; Walterfang, M; Delatycki, MB; Storey, E; Fahey, M; Cooper, S; Lacaze, P; Masters, CL; Velakoulis, D; Bahlo, M; James, PA; Winship, I
Abstract
Mesoderm-derived PDGFRA(+) cells regulate the emergence of hematopoietic stem cells in the dorsal aorta
Nature Cell Biology - 2022-07-28
Chandrakanthan, V; Rorimpandey, P; Zanini, F; Chacon, D; Olivier, J; Joshi, S; Kang, YC; Knezevic, K; Huang, Y; Qiao, Q; Oliver, RA; Unnikrishnan, A; Carter, DR; Lee, B; Brownlee, C; Power, C; Brink, R; Mendez-Ferrer, S; Enikolopov, G; Walsh, W; Göttgens, B; Taoudi, S; Beck, D; Pimanda, JE
Abstract
Enrichment of BTK Leu528Trp mutations in patients with CLL on zanubrutinib: Potential for pirtobrutinib cross resistance
Blood Advances - 2022-07-28
Blombery, P; Thompson, ER; Lew, TE; Tiong, IS; Bennett, R; Cheah, CY; Lewis, KL; Handunnetti, SM; Tang, CPS; Roberts, A; Seymour, JF; Tam, CS
Abstract
ALLSorts: an RNA-Seq subtype classifier for B-cell acute lymphoblastic leukemia
Blood Advances - 2022-07-26
Schmidt, B; Brown, LM; Ryland, GL; Lonsdale, A; Kosasih, HJ; Ludlow, LE; Majewski, IJ; Blombery, P; Ekert, PG; Davidson, NM; Oshlack, A
Abstract
Runx3 drives a CD8(+) T cell tissue residency program that is absent in CD4(+) T cells
Nature Immunology - 2022-07-26
Fonseca, R; Burn, TN; Gandolfo, LC; Devi, S; Park, SL; Obers, A; Evrard, M; Christo, SN; Buquicchio, FA; Lareau, CA; McDonald, KM; Sandford, SK; Zamudio, NM; Zanluqui, NG; Zaid, A; Speed, TP; Satpathy, AT; Mueller, SN; Carbone, FR; Mackay, LK
Abstract
Maternal SMCHD1 regulates Hox gene expression and patterning in the mouse embryo
Nature Communications - 2022-07-25
Benetti, N; Gouil, Q; Tapia Del Fierro, A; Beck, T; Breslin, K; Keniry, A; McGlinn, E; Blewitt, ME
Abstract
Endothelial Caspase-8 prevents fatal necroptotic hemorrhage caused by commensal bacteria
Cell Death & Differentiation - 2022-07-23
Bader, SM; Preston, SP; Saliba, K; Lipszyc, A; Grant, ZL; Mackiewicz, L; Baldi, A; Hempel, A; Clark, MP; Peiris, T; Clow, W; Bjelic, J; Stutz, MD; Arandjelovic, P; TEALE, J; Du, F; Coultas, L; Murphy, JM; Allison, CC; Pellegrini, M; Samson, AL
Abstract
G-CSF receptor deletion amplifies cortical bone dysfunction in mice with STAT3 hyperactivation in osteocytes
Journal of Bone and Mineral Research - 2022-07-20
Isojima, T; Walker, EC; Poulton, IJ; McGregor, NE; Wicks, IP; Gooi, JH; Martin, TJ; Sims, NA
Abstract
Loss of TIP60 (KAT5) abolishes H2AZ lysine 7 acetylation and causes p53, INK4A, and ARF-independent cell cycle arrest
Cell Death & Disease - 2022-07-20
Wichmann, Johannes; Pitt, Catherine; Eccles, Samantha; Garnham, Alexandra L; Li-Wai-Suen, Connie SN; May, Rose; Allan, Elizabeth; Wilcox, Stephen; Herold, Marco J; Smyth, Gordon K; Monahan, Brendon J; Thomas, Tim; Voss, Anne K
Abstract
Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function
Cell Metabolism - 2022-07-19
Blazev, R; Carl, CS; Ng, YK; Molendijk, J; Voldstedlund, CT; Zhao, Y; Xiao, D; Kueh, AJ; Miotto, PM; Haynes, VR; Hardee, JP; Chung, JD; McNamara, JW; Qian, H; Gregorevic, P; Oakhill, JS; Herold, MJ; Jensen, TE; Lisowski, L; Lynch, GS; Dodd, GT; Watt, MJ; Yang, P; Kiens, B; Richter, EA; Parker, BL
Abstract
Genetics of testicular cancer: a review
Current Opinion in Urology - 2022-07-19
Martin, FC; Conduit, C; Loveland, KL; Thomas, B; Lewin, J; Tran, B
Abstract
Maternal SMCHD1 controls both imprinted Xist expression and imprinted X chromosome inactivation
Epigenetics & Chromatin - 2022-07-18
Wanigasuriya, I; Kinkel, SA; Beck, T; Roper, EA; Breslin, K; Lee, HJ; Keniry, A; Ritchie, ME; Blewitt, ME; Gouil, Q
Abstract
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