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Showing results for: AUTHOR - Ekert, PG

Found: 78 results

MLL-TFE3: a novel and aggressive KMT2A fusion identified in infant leukemia Blood Advances - 2020-10-13 Kosasih, HJ; Davidson, NM; Bjelosevic, S; Morrish, E; Brennan, MS; Oshlack, A; Johnstone, RW; Brumatti, G; Khaw, SL; Ekert, PG
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Cotargeting BCL-2 and MCL-1 in high-risk B-ALL Blood Advances - 2020-06-23 Moujalled, DM; Hanna, DT; Hediyeh-Zadeh, S; Pomilio, G; BROWN, L; Litalien, V; Bartolo, R; Fleming, S; Chanrion, M; Banquet, S; Maragno, AL; Kraus-Berthier, L; Schoumacher, M; Mullighan, CG; Georgiou, A; White, CA; Lessene, G; Huang, DCS; Roberts, AW; Geneste, O; Rasmussen, L; Davis, MJ; Ekert, PG; Wei, A; Ng, AP; Khaw, SL
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The application of RNA sequencing for the diagnosis and genomic classification of pediatric acute lymphoblastic leukemia Blood Advances - 2020-03-10 Brown, LM; Lonsdale, A; Zhu, A; Davidson, NM; Schmidt, B; Hawkins, A; Wallach, E; Martin, M; Mechinaud, FM; Khaw, SL; Bartolo, RC; Ludlow, LEA; Challis, J; Brooks, I; Petrovic, V; Venn, NC; Sutton, R; Majewski, IJ; Oshlack, A; Ekert, PG
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Targeted therapy and disease monitoring in CNTRL-FGFR1-driven leukaemia Pediatric Blood & Cancer - 2019-06-28 Brown, LM; Bartolo, RC; Davidson, NM; Schmidt, B; Brooks, I; Challis, J; Petrovic, V; Khuong-Quang, DA; MeChinaud, F; Khaw, SL; Majewski, IJ; Oshlack, A; Ekert, PG
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Integration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer Cancer Biology & Therapeutics - 2018-10-09 Tsoli, M; Wadham, C; Pinese, M; Failes, T; Joshi, S; Mould, E; Yin, JX; Gayevskiy, V; Kumar, A; Kaplan, W; Ekert, PG; Saletta, F; Franshaw, L; Liu, J; Gifford, A; Weber, MA; Rodriguez, M; Cohn, RJ; Arndt, G; Tyrrell, V; Haber, M; Trahair, T; Marshall, GM; McDonald, K; Cowley, MJ; Ziegler, DS
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Clinker: visualising fusion genes detected in RNA-seq data Gigascience - 2018-07-04 Schmidt, BM; Davidson, NM; Hawkins, ADK; Bartolo, R; Majewski, IJ; Ekert, PG; Oshlack, A
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Enhancing venetoclax activity in acute myeloid leukemia by co-targeting MCL1 Leukemia - 2018-02 Teh, TC; Nguyen, NY; Moujalled, DM; Segal, D; Pomilio, G; Rijal, S; Jabbour, A; Cummins, K; Lackovic, K; Blombery, P; Thompson, E; Ekert, PG; Lessene, G; Glaser, SP; Huang, DCS; Roberts, AW; Guthridge, MA; Wei, AH
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Dysregulation of BCL-2 family proteins by leukaemia fusion genes Journal of Biological Chemistry - 2017-09-01 Brown, LM; Hanna, DT; Khaw, SL; Ekert, PG
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Role of the beta Common (betac) family of cytokines in health and disease Cold Spring Harbor Perspectives in Biology - 2017-07-17 Hercus, TR; Kan, WLT; Broughton, SE; Tvorogov, D; Ramshaw, HS; Sandow, JJ; Nero, TL; Dhagat, U; Thompson, EJ; Shing, Ksct; McKenzie, DR; Wilson, NJ; Owczarek, CM; Vairo, G; Nash, AD; Tergaonkar, V; Hughes, T; Ekert, PG; Samuel, MS; Bonder, CS; Grimbaldeston, MA; Parker, MW; Lopez, AF
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High CD123 levels enhance proliferation in response to IL-3, but reduce chemotaxis by downregulating CXCR4 expression Blood Adv - 2017-06-27 Wittwer, NL; Brumatti, G; Marchant, C; Sandow, JJ; Pudney, MK; DOTTORE, M; D'Andrea, RJ; Lopez, AF; Ekert, PG; Ramshaw, HS
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Quantitative proteomic analysis of EZH2 inhibition in acute myeloid leukemia reveals the targets and pathways that precede the induction of cell death Proteomics Clinical Applications - 2017-04-26 Sandow, JJ; Infusini, G; Holik, AZ; Brumatti, G; Averink, TV; Ekert, PG; Webb, AI
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Functionally distinct roles foar different miR-155 expression levels through contrasting effects on gene expression, in acute myeloid leukemia Leukemia - 2017-04 Narayan, N; Morenos, L; Phipson, B; Willis, SN; Brumatti, G; Eggers, S; Lalaoui, N; Brown, LM; Kosasih, HJ; Bartolo, RC; Zhou, L; Catchpoole, D; Saffery, R; Oshlack, A; Goodall, GJ; Ekert, PG
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The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia Sci Transl Med - 2016-05-18 Brumatti, G; Ma, C; Lalaoui, N; Nguyen, NY; Navarro, M; Tanzer, MC; Richmond, J; Ghisi, M; Salmon, JM; Silke, N; Pomilio, G; Glaser, SP; de Valle, E; Gugasyan, R; Gurthridge, MA; Condon, SM; Johnstone, RW; Lock, R; Salvesen, G; Wei, A; Vaux, DL; Ekert, PG; Silke, J
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Targeting p38 or MK2 enhances the anti-leukemic activity of smac-mimetics Cancer Cell - 2016-02-08 Lalaoui, N; Hanggi, K; Brumatti, G; Chau, D; Nguyen, NY; Vasilikos, L; Spilgies, LM; Heckmann, DA; Ma, C; Ghisi, M; Salmon, JM; Matthews, GM; de Valle, E; Moujalled, DM; Menon, MB; Spall, SK; Glaser, SP; Richmond, J; Lock, RB; Condon, SM; Gugasyan, R; Gaestel, M; Guthridge, M; Johnstone, RW; Munoz, L; Wei, A; Ekert, PG; Vaux, DL; Wong, WW; Silke, J
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Cycloheximide can induce Bax/Bak dependent myeloid cell death independently of multiple BH3-only proteins PLoS One - 2016 Goodall, KJ; Finch-Edmondson, ML; van Vuuren, J; Yeoh, GC; Gentle, IE; Vince, JE; Ekert, PG; Vaux, DL; Callus, BA
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Autophagy and AML-food for thought Cell Death Differ - 2016-01 Lalaoui, N; Johnstone, R; Ekert, PG
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The molecular relationships between apoptosis, autophagy and necroptosis Semin Cell Dev Biol - 2015-02-28 Lalaoui, N; Lindqvist, LM; Sandow, JJ; Ekert, PG
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Interleukin-3-mediated regulation of beta-catenin in myeloid transformation and acute myeloid leukemia J Leukoc Biol - 2014-07 Sadras, T; Perugini, M; Kok, CH; Iarossi, DG; Heatley, SL; Brumatti, G; Samuel, MS; To, LB; Lewis, ID; Lopez, AF; Ekert, PG; Ramshaw, HS; D'Andrea, RJ
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RIPK1 regulates RIPK3-MLKL driven systemic inflammation and emergency hematopoiesis. Cell - 2014-05-07 Rickard, JA; O'Donnell, JA; Evans, JM; Lalaoui, N; Poh, AR; Rogers, T; Vince, JE; Lawlor, KE; Ninnis, RL; Anderton, H; Hall, CJ; Spall, SK; Phesse, TJ; Abud, HE; Cengia, LH; Corbin, J; Mifsud, S; Di Rago, L; Metcalft, D; Ernst, M; Dewson, G; Roberts, AW; Alexander, WS; Murphy, JM; Ekert, PG; Masters, SL; Vaux, DL; Croker, BA; Gerlic, M; Silke, J
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ER stress does not cause upregulation and activation of caspase-2 to initiate apoptosis. Cell Death and Differentiation - 2014-03-21 Sandow, JJ; Dorstyn, L; O'Reilly, LA; Tailler, M; Kumar, S; Strasser, A; Ekert, PG
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The oncogenic properties of EWS/WT1 of desmoplastic small round cell tumors are unmasked by loss of p53 in murine embryonic fibroblasts BMC cancer - 2013-12-09 Bandopadhayay, P; Jabbour, AM; Riffkin, C; Salmanidis, M; Gordon, L; Popovski, D; Rigby, L; Ashley, DM; Watkins, DN; Thomas, DM; Algar, E; Ekert, PG
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Role of p53 in cAMP/PKA pathway mediated apoptosis. Apoptosis : an international journal on programmed cell death - 2013-12 Rahimi, A; Lee, YY; Abdella, H; Doerflinger, M; Gangoda, L; Srivastava, R; Xiao, K; Ekert, PG; Puthalakath, H
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HoxA9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of HoxA9-dependent leukemia Oncotarget - 2013-11 Brumatti, G; Salmanidis, M; Kok, CH; Bilardi, RA; Sandow, JJ; Silke, N; Mason, K; Visser, J; Jabbour, AM; Glaser, SP; Okamoto, T; Bouillet, P; D'Andrea, RJ; Ekert, PG
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Seeking a MCL-1 Inhibitor Cell Death Differ - 2013-11 Brumatti, G; Ekert, PG
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Akt1 is the principal Akt isoform regulating apoptosis in limiting cytokine concentrations CELL DEATH AND DIFFERENTIATION - 2013-10 Green, BD; Jabbour, AM; Sandow, JJ; Riffkin, CD; Masouras, D; Daunt, CP; Salmanidis, M; Brumatti, G; Hemmings, BA; Guthridge, MA; Pearson, RB; Ekert, PG
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