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Showing results for: AUTHOR - Gray, DHD

Found: 32 results

Unresponsiveness to inhaled antigen is governed by conventional dendritic cells and overridden during infection by monocytes Science Immunology - 2020-10-09 Bedford, JG; Heinlein, M; Garnham, AL; Nguyen, THO; Loudovaris, T; Ge, C; Mannering, SI; ELLIOTT, M; Tangye, SG; Kedzierska, K; Gray, DHD; Heath, WR; Wakim, LM
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Ubiquitination of MHC Class II is required for development of regulatory but not conventional CD4(+) T cells J Immunol - 2020-08-03 Liu, H; Wilson, KR; Schriek, P; Macri, C; Blum, AB; Francis, L; Heinlein, M; Nataraja, C; Harris, J; Jones, SA; Gray, DHD; Villadangos, JA; Mintern, JD
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MCL-1 is essential for survival but dispensable for metabolic fitness of FOXP3(+) regulatory T cells Cell Death and Differentiation - 2020-07-01 Teh, CE; Robbins, AK; Henstridge, DC; Dewson, G; Diepstraten, ST; Kelly, G; Febbraio, MA; Gabriel, SS; O'Reilly, LA; Strasser, A; Gray, DHD
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Dual targeting of CDK4/6 and BCL2 pathways augments tumor response in estrogen receptor positive breast cancer Clinical Cancer Research - 2020-04-03 Whittle, JR; Vaillant, F; Surgenor, E; Policheni, AN; Giner, G; Capaldo, BD; Chen, HR; Liu, HK; Dekkers, JF; Sachs, N; Clevers, H; Fellowes, A; Green, T; Xu, H; Fox, SB; Herold, MJ; Smyth, GK; Gray, DHD; Visvader, JE; Lindeman, GJ
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Deep profiling of apoptotic pathways with mass cytometry identifies a synergistic drug combination for killing myeloma cells Cell Death and Differentiation - 2020-01-27 Teh, CE; Gong, JN; Segal, D; Tan, T; Vandenberg, CJ; Fedele, PL; Low, MSY; Grigoriadis, G; Harrison, SJ; Strasser, A; Roberts, AW; Huang, DCS; Nolan, GP; Gray, DHD; Ko, ME
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A phase 1b dose-escalation and expansion study of the BCL-2 inhibitor venetoclax combined with tamoxifen in ER and BCL-2-positive metastatic breast cancer Cancer Discovery - 2019-12-05 Lok, SW; Whittle, JR; Vaillant, F; Teh, CE; Lo, LL; Policheni, AN; Bergin, ART; Desai, J; Ftouni, S; Gandolfo, LC; Liew, D; Liu, HK; Mann, GB; Moodie, K; Murugasu, A; Pal, B; Roberts, AW; Rosenthal, MA; Shackleton, K; Silva, MJ; Siow, ZR; Smyth, GK; Taylor, L; Travers, A; Yeo, B; Yeung, MM; Zivanovic Bujak, A; Dawson, SJ; Gray, DHD; Visvader, JE; Lindeman, GJ
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The 2019 Lasker Award: T cells and B cells, whose life and death are essential for function of the immune system Cell Death and Differentiation - 2019-12 Gray, DHD; Vaux, DL; Strasser, A
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Deletion of self-reactive CCR7- thymocytes in the absence of MHC expression on thymic epithelial cells Cell Death and Differentiation - 2019-12 Wirasinha, RC; Chan, A; Yap, JY; Hu, DY; Teh, CE; Gray, DHD; Goodnow, CC; Daley, SR
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CARD11 is dispensable for homeostatic responses and suppressive activity of peripherally-induced FOXP3+ regulatory T cells Immunology and Cell Biology - 2019-09 Policheni, A; Horikawa, K; Milla, L; Kofler, J; Bouillet, P; Belz, GT; O'Reilly, LA; Goodnow, CC; Strasser, A; Gray, DHD
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Acquisition of the recurrent Gly101Val mutation in BCL2 confers resistance to venetoclax in patients with progressive chronic lymphocytic leukemia Cancer Discovery - 2019-03 Blombery, P; Anderson, MA; Gong, JN; Thijssen, R; Birkinshaw, RW; Thompson, ER; Teh, CE; Nguyen, T; Xu, Z; Flensburg, C; Lew, TE; Majewski, IJ; Gray, DHD; Westerman, DA; Tam, CS; Seymour, JF; Czabotar, PE; Huang, DCS; Roberts, AW
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PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia Blood - 2019-02-12 McRae, HM; Garnham, AL; Hu, Y; Witkowski, MT; Corbett, MA; Dixon, MP; May, RE; Sheikh, BN; Chiang, W; Kueh, AJ; Nguyen, TA; Man, K; Gloury, R; Aubrey, BJ; Policheni, A; Di Rago, L; Alexander, WS; Gray, DHD; Strasser, A; Hawkins, ED; Wilcox, S; Gecz, J; Kallies, A; McCormack, MP; Smyth, GK; Voss, AK; Thomas, T
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The mitochondrial apoptotic effectors BAX/BAK activate caspase-3 and -7 to trigger NLRP3 inflammasome and caspase-8 driven IL-1beta activation Cell Reports - 2018-11-27 Vince, JE; De Nardo, D; Gao, W; Vince, AJ; Hall, C; McArthur, K; Simpson, D; Vijayaraj, S; Lindqvist, LM; Bouillet, P; Rizzacasa, MA; Man, SM; Silke, J; Masters, SL; Lessene, G; Huang, DCS; Gray, DHD; Kile, BT; Shao, F; Lawlor, KE
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VDAC2 enables BAX to mediate apoptosis and limit tumor development Nature Communications - 2018-11-26 Chin, HS; Li, MX; Tan, IKL; Ninnis, RL; Reljic, B; Scicluna, K; Dagley, LF; Sandow, JJ; Kelly, GL; Samson, AL; Chappaz, S; Khaw, SL; Chang, C; Morokoff, A; Brinkmann, K; Webb, A; Hockings, C; Hall, CM; Kueh, AJ; Ryan, MT; Kluck, RM; Bouillet, P; Herold, MJ; Gray, DHD; Huang, DCS; van Delft, MF; Dewson, G
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Dynamic molecular monitoring reveals that SWI-SNF mutations mediate resistance to ibrutinib plus venetoclax in mantle cell lymphoma Nature Medicine - 2018-11-19 Agarwal, R; Chan, YC; Tam, CS; Hunter, T; Vassiliadis, D; Teh, CE; Thijssen, R; Yeh, P; Wong, SQ; Ftouni, S; Lam, EYN; Anderson, MA; Pott, C; Gilan, O; Bell, CC; Knezevic, K; Blombery, P; Rayeroux, K; Zordan, A; Li, J; Huang, DCS; Wall, M; Seymour, JF; Gray, DHD; Roberts, AW; Dawson, MA; Dawson, SJ
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How do thymic epithelial cells die? Cell Death and Differentiation - 2018 Jain, R; Mintern, JD; Tan, I; Dewson, G; Strasser, A; Gray, DHD
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Thymospheres are formed by mesenchymal cells with the potential to generate adipocytes, but not epithelial cells Cell Reports - 2017-10-24 Sheridan, JM; Keown, A; Policheni, A; Roesley, SNA; Rivlin, N; Kadouri, N; Ritchie, ME; Jain, R; Abramson, J; Heng, TSP; Gray, DHD
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A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice Blood - 2017-09-29 Jain, R; Sheridan, JM; Policheni, A; Heinlein, M; Gandolfo, LC; Dewson, G; Smyth, GK; Sansom, SN; Fu, NY; Visvader, JE; Hollander, GA; Strasser, A; Gray, DHD
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Combined immune checkpoint blockade as a therapeutic strategy for BRCA1-mutated breast cancer Science Translational Medicine - 2017-06-07 Nolan, E; Savas, P; Policheni, AN; Darcy, PK; Vaillant, F; Mintoff, CP; Dushyanthen, S; Mansour, M; Pang, JB; Fox, SB; Kathleen Cuningham Foundation Consortium for Research into Familial Breast, Cancer; Perou, CM; Visvader, JE; Gray, DHD; Loi, S; Lindeman, GJ
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Cell death and thymic tolerance Immunology Reviews - 2017-05 Daley, SR; Teh, C; Hu, DY; Strasser, A; Gray, DHD
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Homeostatic control of regulatory T cell diversity Nature Reviews Immunology - 2014-01-31 Liston, A; Gray, DHD
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Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3(+) regulatory T cells NATURE IMMUNOLOGY - 2013-09 Pierson, W; Cauwe, B; Policheni, A; Schlenner, SM; Franckaert, D; Berges, J; Humblet-Baron, S; Schonefeldt, S; Herold, MJ; Hildeman, D; Strasser, A; Bouillet, P; Lu, LF; Matthys, P; Freitas, AA; Luther, RJ; Weaver, CT; Dooley, J; Gray, DHD; Liston, A
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p53 Efficiently Suppresses Tumor Development in the Complete Absence of Its Cell-Cycle Inhibitory and Proapoptotic Effectors p21, Puma, and Noxa CELL REPORTS - 2013-05 Valente, LJ; Gray, DHD; Michalak, EM; Pinon-Hofbauer, J; Egle, A; Scott, CL; Janic, A; Strasser, A
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Proapoptotic Bak and Bax guard against fatal systemic and organ-specific autoimmune disease PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA - 2013-02-12 Mason, KD; Lin, A; Robb, L; Josefsson, EC; Henley, KJ; Gray, DHD; Kile, BT; Roberts, AW; Strasser, A; Huang, DCS; Waring, P; O'Reilly, LA
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Aire mediates thymic expression and tolerance of pancreatic antigens via an unconventional transcriptional mechanism EUROPEAN JOURNAL OF IMMUNOLOGY - 2013-01 Danso-Abeam, D; Staats, KA; Franckaert, D; Van Den Bosch, L; Liston, A; Gray, DHD; Dooley, J
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Elevated Mcl-1 inhibits thymocyte apoptosis and alters thymic selection CELL DEATH AND DIFFERENTIATION - 2012-12 Campbell, KJ; Gray, DHD; Anstee, N; Strasser, A; Cory, S
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