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Showing results for: AUTHOR - Johnstone, RW

Found: 48 results

MLL-TFE3: a novel and aggressive KMT2A fusion identified in infant leukemia Blood Advances - 2020-10-13 Kosasih, HJ; Davidson, NM; Bjelosevic, S; Morrish, E; Brennan, MS; Oshlack, A; Johnstone, RW; Brumatti, G; Khaw, SL; Ekert, PG
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CDK13 cooperates with CDK12 to control global RNA polymerase II processivity Science Advances - 2020 Fan, Z; Devlin, JR; Hogg, SJ; Doyle, MA; Harrison, PF; Todorovski, I; Cluse, LA; Knight, DA; Sandow, JJ; Gregory, G; Fox, A; Beilharz, TH; Kwiatkowski, N; Scott, NE; Vidakovic, AT; Kelly, GP; Svejstrup, JQ; Geyer, M; Gray, NS; Vervoort, SJ; Johnstone, RW
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Interconversion between tumorigenic and differentiated states in acute myeloid leukemia Cell Stem Cell - 2019-08-01 McKenzie, MD; Ghisi, M; Oxley, EP; Ngo, S; Cimmino, L; Esnault, C; Liu, R; Salmon, JM; Bell, CC; Ahmed, N; Erlichster, M; Witkowski, MT; Liu, GJ; Chopin, M; Dakic, A; Simankowicz, E; Pomilio, G; Vu, T; Krsmanovic, P; Su, S; Tian, L; Baldwin, TM; Zalcenstein, DA; DiRago, L; Wang, S; Metcalf, D; Johnstone, RW; Croker, BA; Lancaster, GI; Murphy, AJ; Naik, SH; Nutt, SL; Pospisil, V; Schroeder, T; Wall, M; Dawson, MA; Wei, AH; de The, H; Ritchie, ME; Zuber, J; Dickins, RA
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Antagonism of IAPs enhances CAR T-cell efficacy Cancer Immunol Research - 2019-02 Michie, J; Beavis, PA; Freeman, AJ; Vervoort, SJ; Ramsbottom, KM; Narasimhan, V; Lelliott, EJ; Lalaoui, N; Ramsay, RG; Johnstone, RW; Silke, J; Darcy, PK; Voskoboinik, I; Kearney, CJ; Oliaro, J
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Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth Nature - 2018-08-01 Baell, JB; Leaver, DJ; Hermans, SJ; Kelly, GL; Brennan, MS; Downer, NL; Nguyen, N; Wichmann, J; McRae, HM; Yang, Y; Cleary, B; Lagiakos, HR; Mieruszynski, S; Pacini, G; Vanyai, HK; Bergamasco, MI; May, RE; Davey, BK; Morgan, KJ; Sealey, AJ; Wang, B; Zamudio, N; Wilcox, S; Garnham, AL; Sheikh, BN; Aubrey, BJ; Doggett, K; Chung, MC; de Silva, M; Bentley, J; Pilling, P; Hattarki, M; Dolezal, O; Dennis, ML; Falk, H; Ren, B; Charman, SA; White, KL; Rautela, J; Newbold, A; Hawkins, ED; Johnstone, RW; Huntington, ND; Peat, TS; Heath, JK; Strasser, A; Parker, MW; Smyth, GK; Street, IP; Monahan, BJ; Voss, AK; Thomas, T
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JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemias Genes & Development - 2018-06-01 Kim, SK; Knight, DA; Jones, LR; Vervoort, S; Ng, AP; Seymour, JF; Bradner, JE; Waibel, M; Kats, L; Johnstone, RW
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Tumor immune evasion arises through loss of TNF sensitivity Science Immunology - 2018-05-18 Kearney, CJ; Vervoort, SJ; Hogg, SJ; Ramsbottom, KM; Freeman, AJ; Lalaoui, N; Pijpers, L; Michie, J; Brown, KK; Knight, DA; Sutton, V; Beavis, PA; Voskoboinik, I; Darcy, PK; Silke, J; Trapani, JA; Johnstone, RW; Oliaro, J
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Epigenetic targeting of Notch1 driven transcription using the HDACi panobinostat is a potential therapy against T cell acute lymphoblastic leukemia Leukemia - 2017-09-15 Waibel, M; Vervoort, SJ; Kong, IY; Heinzel, S; Ramsbottom, KM; Martin, BP; Hawkins, ED; Johnstone, RW
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Genomic characterisation of Emu-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene Nat Commun - 2017-03-06 Lefebure, M; Tothill, RW; Kruse, E; Hawkins, ED; Shortt, J; Matthews, GM; Gregory, GP; Martin, BP; Kelly, MJ; Todorovski, I; Doyle, MA; Lupat, R; Li, J; Schroeder, J; Wall, M; Craig, S; Poortinga, G; Cameron, D; Bywater, M; Kats, L; Gearhart, MD; Bardwell, VJ; Dickins, RA; Hannan, RD; Papenfuss, AT; Johnstone, RW
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Epigenetic control of mitochondrial cell death through PACS1-mediated regulation of BAX/BAK oligomerization Cell Death and Differentiation - 2017 Brasacchio, D; Alsop, AE; Noori, T; Lufti, M; Iyer, S; Simpson, KJ; Bird, PI; Kluck, RM; Johnstone, RW; Trapani, JA
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In the Midst of Life-Cell Death: What Is It, What Is It Good for, and How to Study It Cold Spring Harb Protoc - 2016-12-01 Silke, J; Johnstone, RW
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T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments Nature - 2016-10-27 Hawkins, ED; Duarte, D; Akinduro, O; Khorshed, RA; Passaro, D; Nowicka, M; Straszkowski, L; Scott, MK; Rothery, S; Ruivo, N; Foster, K; Waibel, M; Johnstone, RW; Harrison, SJ; Westerman, DA; Quach, H; Gribben, J; Robinson, MD; Purton, LE; Bonnet, D; Lo Celso, C
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A community-based model of rapid autopsy in end-stage cancer patients Nat Biotechnol - 2016-09-12 Alsop, K; Thorne, H; Sandhu, S; Hamilton, A; Mintoff, C; Christie, E; Spruyt, O; Williams, S; McNally, O; Mileshkin, L; Ananda, S; Hallo, J; Loi, S; Scott, C; Savas, P; Devereux, L; O'Brien, P; Gunawardena, S; Hampson, C; Strachan, K; Jaravaza, RD; Francis, V; Young, G; Ranson, D; Samaranayake, R; Stevens, D; Boyle, S; Fedele, C; Topp, M; Ho, G; Teo, ZL; Taylor, RA; Papargiris, MM; Lawrence, MG; Wang, H; Risbridger, GP; Haynes, NM; Medon, M; Johnstone, RW; Vidacs, E; Arnau, GM; Vergara, IA; Papenfuss, AT; McArthur, G; Waring, P; Carvosso, S; Angel, C; Gyorki, D; Solomon, B; Mitchell, G; Shanley, S; Francis, PA; Dawson, SJ; Haffenden, A; Tidball, E; Volchek, M; Pyman, J; Madadin, M; Leditschke, J; Cordner, S; Melbourne Melanoma, Project; Australian Ovarian Cancer Study, Group; Kathleen Cuningham Foundation Consortium for Research into Familial Breast, Cancer; Shackleton, M; Bowtell, DD
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Id2 and E proteins orchestrate the initiation and maintenance of MLL-rearranged acute myeloid leukemia Cancer Cell - 2016-07-11 Ghisi, M; Kats, L; Masson, F; Li, J; Kratina, T; Vidacs, E; Gilan, O; Doyle, MA; Newbold, A; Bolden, JE; Fairfax, KA; de Graaf, CA; Firth, M; Zuber, J; Dickins, RA; Corcoran, LM; Dawson, MA; Belz, GT; Johnstone, RW
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CD271 expression on patient melanoma cells is unstable and unlinked to tumorigenicity Cancer Research - 2016-06-20 Boyle, SE; Fedele, CG; Corbin, V; Wybacz, E; Szeto, P; Lewin, J; Young, RJ; Wong, A; Fuller, R; Spillane, J; Speakman, D; Donahoe, S; Pohl, M; Gyorki, D; Henderson, MA; Johnstone, RW; Papenfuss, AT; Shackleton, M
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Functional interdependence of BRD4 and DOT1L in MLL leukemia Nature Structural & Molecular Biology - 2016-06-13 Gilan, O; Lam, EY; Becher, I; Lugo, D; Cannizzaro, E; Joberty, G; Ward, A; Wiese, M; Fong, CY; Ftouni, S; Tyler, D; Stanley, K; MacPherson, L; Weng, CF; Chan, YC; Ghisi, M; Smil, D; Carpenter, C; BROWN, P; Garton, N; Blewitt, ME; Bannister, AJ; Kouzarides, T; Huntly, BJ; Johnstone, RW; Drewes, G; Dawson, SJ; Arrowsmith, CH; Grandi, P; Prinjha, RK; Dawson, MA
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The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia Sci Transl Med - 2016-05-18 Brumatti, G; Ma, C; Lalaoui, N; Nguyen, NY; Navarro, M; Tanzer, MC; Richmond, J; Ghisi, M; Salmon, JM; Silke, N; Pomilio, G; Glaser, SP; de Valle, E; Gugasyan, R; Gurthridge, MA; Condon, SM; Johnstone, RW; Lock, R; Salvesen, G; Wei, A; Vaux, DL; Ekert, PG; Silke, J
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Scribble acts as an oncogene in Emu-myc-driven lymphoma Oncogene - 2016-03-03 Hawkins, ED; Oliaro, J; Ramsbottom, KM; Newbold, A; Humbert, PO; Johnstone, RW; Russell, SM
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Therapeutic response to non-genotoxic activation of p53 by nutlin3a is driven by puma-mediated apoptosis in lymphoma cells Cell Rep - 2016-03-01 Valente, LJ; Aubrey, BJ; Herold, MJ; Kelly, GL; Happo, L; Scott, CL; Newbold, A; Johnstone, RW; Huang, DC; Vassilev, LT; Strasser, A
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Targeting p38 or MK2 enhances the anti-leukemic activity of smac-mimetics Cancer Cell - 2016-02-08 Lalaoui, N; Hanggi, K; Brumatti, G; Chau, D; Nguyen, NY; Vasilikos, L; Spilgies, LM; Heckmann, DA; Ma, C; Ghisi, M; Salmon, JM; Matthews, GM; de Valle, E; Moujalled, DM; Menon, MB; Spall, SK; Glaser, SP; Richmond, J; Lock, RB; Condon, SM; Gugasyan, R; Gaestel, M; Guthridge, M; Johnstone, RW; Munoz, L; Wei, A; Ekert, PG; Vaux, DL; Wong, WW; Silke, J
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UV-associated mutations underlie the etiology of MCV-negative Merkel cell carcinomas Cancer Research - 2015-12-15 Wong, SQ; Waldeck, K; Vergara, IA; Schroder, J; Madore, J; Wilmott, JS; Colebatch, AJ; De Paoli-Iseppi, R; Li, J; Lupat, R; Semple, T; Arnau, GM; Fellowes, A; Leonard, JH; Hruby, G; Mann, GJ; Thompson, JF; Cullinane, C; Johnston, M; Shackleton, M; Sandhu, S; Bowtell, DD; Johnstone, RW; Fox, SB; McArthur, GA; Papenfuss, AT; Scolyer, RA; Gill, AJ; Hicks, RJ; Tothill, RW
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BET inhibitor resistance emerges from leukaemia stem cells Nature - 2015-09-24 Fong, CY; Gilan, O; Lam, EY; Rubin, AF; Ftouni, S; Tyler, D; Stanley, K; Sinha, D; Yeh, P; Morison, J; Giotopoulos, G; Lugo, D; Jeffrey, P; Lee, SC; Carpenter, C; Gregory, R; Ramsay, RG; Lane, SW; Abdel-Wahab, O; Kouzarides, T; Johnstone, RW; Dawson, SJ; Huntly, BJ; Prinjha, RK; Papenfuss, AT; Dawson, MA
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Manipulation of B-cell responses with histone deacetylase inhibitors Nat Commun - 2015 Waibel, M; Christiansen, AJ; Hibbs, ML; Shortt, J; Jones, SA; Simpson, I; Light, A; O'Donnell, K; MORAND, EF; Tarlinton, DM; Johnstone, RW; Hawkins, ED
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The Drug Vehicle and Solvent N-Methylpyrrolidone Is an Immunomodulator and Antimyeloma Compound Cell Rep - 2014-05-07 Shortt, J; Hsu, AK; Martin, BP; Doggett, K; Matthews, GM; Doyle, MA; Ellul, J; Jockel, TE; Andrews, DM; Hogg, SJ; Reitsma, A; Faulkner, D; Bergsagel, PL; Chesi, M; Heath, JK; Denny, WA; Thompson, PE; Neeson, PJ; Ritchie, DS; McArthur, GA; Johnstone, RW
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Socrates: Identification of genomic rearrangements in tumour genomes by re-aligning soft clipped reads Bioinformatics - 2014-01-02 Schroder, J; Hsu, A; Boyle, SE; Macintyre, G; Cmero, M; Tothill, RW; Johnstone, RW; Shackleton, M; Papenfuss, AT
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