Search

Showing results for: AUTHOR - Kelly, GL

Found: 29 results

BCL-XL inhibition by BH3-mimetic drugs induces apoptosis in models of Epstein-Barr virus-associated T/NK-cell lymphoma Blood Advances - 2020-10-13 Sejic, N; George, LC; Tierney, RJ; Chang, C; Kondrashova, O; MacKinnon, RN; Lan, P; Bell, AI; Lessene, G; Long, HM; Strasser, A; Shannon-Lowe, C; Kelly, GL
Link to Open Access at Publisher's Site Download PDF
Potent efficacy of MCL-1 inhibitor-based therapies in preclinical models of mantle cell lymphoma Oncogene - 2020-02 Dengler, MA; Teh, CE; Thijssen, R; Gangoda, L; Lan, P; Herold, MJ; Gray, DH; Kelly, GL; Roberts, AW; Adams, JM
Link to Publisher's Version Download Author Manuscript
BCL-W is dispensable for the sustained survival of select Burkitt lymphoma and diffuse large B-cell lymphoma cell lines Blood Advances - 2020-01-28 Diepstraten, ST; Chang, C; Tai, L; Gong, JN; Lan, P; Dowell, AC; Taylor, GS; Strasser, A; Kelly, GL
Link to Open Access at Publisher's Site
Toward targeting antiapoptotic MCL-1 for cancer therapy Annual Review of Cancer Biology - 2020 Kelly, GL; Strasser, A
Link to Open Access at Publisher's Site
EBV BCL-2 homologue BHRF1 drives chemoresistance and lymphomagenesis by inhibiting multiple cellular pro-apoptotic proteins Cell Death and Differentiation - 2019-10-23 Fitzsimmons, L; Cartlidge, R; Chang, C; Sejic, N; Galbraith, LCA; Suraweera, CD; Croom-Carter, D; Dewson, G; Tierney, RJ; Bell, AI; Shannon-Lowe, C; Herold, MJ; Rickinson, AB; Colman, PM; Huang, DCS; Strasser, A; Kvansakul, M; Rowe, M; Kelly, GL
Link to Publisher's Version
Discussion of some "knowns" and some "unknowns" about the tumour suppressor p53 Journal of Molecular Cell Biology - 2019-03 Lieschke, E; Wang, Z; Kelly, GL; Strasser, A
Link to Open Access at Publisher's Site
BH3-mimetic drugs: blazing the trail for new cancer medicines Cancer Cell - 2018-12-10 Merino, D; Kelly, GL; Lessene, G; Wei, AH; Roberts, AW; Strasser, A
Link to Publisher's Version
VDAC2 enables BAX to mediate apoptosis and limit tumor development Nature Communications - 2018-11-26 Chin, HS; Li, MX; Tan, IKL; Ninnis, RL; Reljic, B; Scicluna, K; Dagley, LF; Sandow, JJ; Kelly, GL; Samson, AL; Chappaz, S; Khaw, SL; Chang, C; Morokoff, A; Brinkmann, K; Webb, A; Hockings, C; Hall, CM; Kueh, AJ; Ryan, MT; Kluck, RM; Bouillet, P; Herold, MJ; Gray, DHD; Huang, DCS; van Delft, MF; Dewson, G
Link to Open Access at Publisher's Site
Mutant TRP53 exerts a target gene-selective dominant-negative effect to drive tumor development Genes & Development - 2018-11-01 Aubrey, BJ; Janic, A; Chen, Y; Chang, C; Lieschke, EC; Diepstraten, ST; Kueh, AJ; Bernardini, JP; Dewson, G; O'Reilly, LA; Whitehead, L; Voss, AK; Smyth, GK; Strasser, A; Kelly, GL
Link to Publisher's Version
Humanized Mcl-1 mice enable accurate pre-clinical evaluation of MCL-1 inhibitors destined for clinical use Blood - 2018-10 Brennan, MS; Chang, C; Tai, L; Lessene, G; Strasser, A; Dewson, G; Kelly, GL; Herold, MJ
Link to Publisher's Version
Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth Nature - 2018-08-01 Baell, JB; Leaver, DJ; Hermans, SJ; Kelly, GL; Brennan, MS; Downer, NL; Nguyen, N; Wichmann, J; McRae, HM; Yang, Y; Cleary, B; Lagiakos, HR; Mieruszynski, S; Pacini, G; Vanyai, HK; Bergamasco, MI; May, RE; Davey, BK; Morgan, KJ; Sealey, AJ; Wang, B; Zamudio, N; Wilcox, S; Garnham, AL; Sheikh, BN; Aubrey, BJ; Doggett, K; Chung, MC; de Silva, M; Bentley, J; Pilling, P; Hattarki, M; Dolezal, O; Dennis, ML; Falk, H; Ren, B; Charman, SA; White, KL; Rautela, J; Newbold, A; Hawkins, ED; Johnstone, RW; Huntington, ND; Peat, TS; Heath, JK; Strasser, A; Parker, MW; Smyth, GK; Street, IP; Monahan, BJ; Voss, AK; Thomas, T
Link to Publisher's Version Download Author Manuscript
How does p53 induce apoptosis and how does this relate to p53-mediated tumour suppression? Cell Death and Differentiation - 2017-11-17 Aubrey, BJ; Kelly, GL; Janic, A; Herold, MJ; Strasser, A
Link to Publisher's Version
EBV and Apoptosis: The Viral Master Regulator of Cell Fate? Viruses - 2017-11-13 Fitzsimmons, L; Kelly, GL
Link to Open Access at Publisher's Site Download PDF
Coordinated repression of BIM and PUMA by Epstein-Barr virus latent genes maintains the survival of Burkitt lymphoma cells Cell Death and Differentiation - 2017-09-29 Fitzsimmons, L; Boyce, AJ; Wei, W; Chang, C; Croom-Carter, D; Tierney, RJ; Herold, MJ; Bell, AI; Strasser, A; Kelly, GL; Rowe, M
Link to Open Access at Publisher's Site
ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress DNA Repair - 2017-06-17 Liu, R; KING, A; Hoch, NC; Chang, C; Kelly, GL; Deans, AJ; Heierhorst, J
Link to Open Access at Publisher's Site
The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models Nature - 2016-10-19 Kotschy, A; Szlavik, Z; Murray, J; Davidson, J; Maragno, AL; Le Toumelin-Braizat, G; Chanrion, M; Kelly, GL; Gong, JN; Moujalled, DM; Bruno, A; Csekei, M; Paczal, A; Szabo, ZB; Sipos, S; Radics, G; Proszenyak, A; Balint, B; Ondi, L; Blasko, G; Robertson, A; Surgenor, A; Dokurno, P; Chen, I; Matassova, N; Smith, J; Pedder, C; Graham, C; Studeny, A; Lysiak-Auvity, G; Girard, AM; Grave, F; Segal, D; Riffkin, CD; Pomilio, G; Galbraith, LC; Aubrey, BJ; Brennan, MS; Herold, MJ; Chang, C; Guasconi, G; Cauquil, N; Melchiore, F; Guigal-Stephan, N; Lockhart, B; Colland, F; Hickman, JA; Roberts, AW; Huang, DC; Wei, AH; Strasser, A; Lessene, G; Geneste, O
Link to Publisher's Version Download Author Manuscript
BET inhibition represses miR17-92 to drive BIM-initiated apoptosis of normal and transformed hematopoietic cells Leukemia - 2016-03-08 Xu, Z; Sharp, PP; Yao, Y; Segal, D; Ang, CH; Khaw, SL; Aubrey, BJ; Gong, J; Kelly, GL; Herold, MJ; Strasser, A; Roberts, AW; Alexander, WS; Burns, CJ; Huang, DC; Glaser, SP
Link to Publisher's Version Download Author Manuscript
Re-activation of mitochondrial apoptosis inhibits T-cell lymphoma survival and treatment resistance Leukemia - 2016-03-08 Spinner, S; Crispatzu, G; Yi, JH; Munkhbaatar, E; MAYER, P; Hockendorf, U; Muller, N; Li, Z; Schader, T; Bendz, H; Hartmann, S; Yabal, M; Pechloff, K; Heikenwalder, M; Kelly, GL; Strasser, A; Peschel, C; Hansmann, ML; Ruland, J; Keller, U; Newrzela, S; Herling, M; Jost, PJ
Link to Publisher's Version
Therapeutic response to non-genotoxic activation of p53 by nutlin3a is driven by puma-mediated apoptosis in lymphoma cells Cell Rep - 2016-03-01 Valente, LJ; Aubrey, BJ; Herold, MJ; Kelly, GL; Happo, L; Scott, CL; Newbold, A; Johnstone, RW; Huang, DC; Vassilev, LT; Strasser, A
Link to Open Access at Publisher's Site
The transcription factor ASCIZ and its target DYNLL1 are essential for the development and expansion of MYC-driven B Cell lymphoma Cell Rep - 2016-02 Wong, DM; Li, L; Jurado, S; KING, A; Bamford, R; Wall, M; Walia, MK; Kelly, GL; Walkley, CR; Tarlinton, DM; Strasser, A; Heierhorst, J
Link to Open Access at Publisher's Site
MCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL Cell Death Dis - 2016 Vikstrom, IB; Slomp, A; Carrington, EM; Moesbergen, LM; Chang, C; Kelly, GL; Glaser, SP; Jansen, JH; Leusen, JH; Strasser, A; Huang, DC; Lew, AM; Peperzak, V; Tarlinton, DM
Link to Open Access at Publisher's Site
Tumor-suppressor functions of the TP53 pathway Cold Spring Harb Perspect Med - 2016 Aubrey, BJ; Strasser, A; Kelly, GL
Link to Publisher's Version
Critical B-lymphoid cell intrinsic role of endogenous MCL-1 in c-MYC-induced lymphomagenesis Cell Death Dis - 2016 Grabow, S; Kelly, GL; Delbridge, AR; Kelly, PN; Bouillet, P; Adams, JM; Strasser, A
Link to Open Access at Publisher's Site
An Inducible Lentiviral Guide RNA Platform Enables the Identification of Tumor-Essential Genes and Tumor-Promoting Mutations In Vivo Cell Rep - 2015-02-24 Aubrey, BJ; Kelly, GL; Kueh, AJ; Brennan, MS; O'Connor, L; Milla, L; Wilcox, S; Tai, L; Strasser, A; Herold, MJ
Link to Open Access at Publisher's Site
Impact of the combined loss of BOK, BAX and BAK on the hematopoietic system is slightly more severe than compound loss of BAX and BAK Cell Death Dis - 2015 Ke, F; Grabow, S; Kelly, GL; Lin, A; O'Reilly, LA; Strasser, A
Link to Open Access at Publisher's Site

An error has occurred. This application may no longer respond until reloaded. Reload 🗙