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Showing results for: AUTHOR - Khaw, SL

Found: 18 results

MLL-TFE3: a novel and aggressive KMT2A fusion identified in infant leukemia Blood Advances - 2020-10-13 Kosasih, HJ; Davidson, NM; Bjelosevic, S; Morrish, E; Brennan, MS; Oshlack, A; Johnstone, RW; Brumatti, G; Khaw, SL; Ekert, PG
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Cotargeting BCL-2 and MCL-1 in high-risk B-ALL Blood Advances - 2020-06-23 Moujalled, DM; Hanna, DT; Hediyeh-Zadeh, S; Pomilio, G; BROWN, L; Litalien, V; Bartolo, R; Fleming, S; Chanrion, M; Banquet, S; Maragno, AL; Kraus-Berthier, L; Schoumacher, M; Mullighan, CG; Georgiou, A; White, CA; Lessene, G; Huang, DCS; Roberts, AW; Geneste, O; Rasmussen, L; Davis, MJ; Ekert, PG; Wei, A; Ng, AP; Khaw, SL
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The application of RNA sequencing for the diagnosis and genomic classification of pediatric acute lymphoblastic leukemia Blood Advances - 2020-03-10 Brown, LM; Lonsdale, A; Zhu, A; Davidson, NM; Schmidt, B; Hawkins, A; Wallach, E; Martin, M; Mechinaud, FM; Khaw, SL; Bartolo, RC; Ludlow, LEA; Challis, J; Brooks, I; Petrovic, V; Venn, NC; Sutton, R; Majewski, IJ; Oshlack, A; Ekert, PG
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Targeted therapy and disease monitoring in CNTRL-FGFR1-driven leukaemia Pediatric Blood & Cancer - 2019-06-28 Brown, LM; Bartolo, RC; Davidson, NM; Schmidt, B; Brooks, I; Challis, J; Petrovic, V; Khuong-Quang, DA; MeChinaud, F; Khaw, SL; Majewski, IJ; Oshlack, A; Ekert, PG
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VDAC2 enables BAX to mediate apoptosis and limit tumor development Nature Communications - 2018-11-26 Chin, HS; Li, MX; Tan, IKL; Ninnis, RL; Reljic, B; Scicluna, K; Dagley, LF; Sandow, JJ; Kelly, GL; Samson, AL; Chappaz, S; Khaw, SL; Chang, C; Morokoff, A; Brinkmann, K; Webb, A; Hockings, C; Hall, CM; Kueh, AJ; Ryan, MT; Kluck, RM; Bouillet, P; Herold, MJ; Gray, DHD; Huang, DCS; van Delft, MF; Dewson, G
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Dysregulation of BCL-2 family proteins by leukaemia fusion genes Journal of Biological Chemistry - 2017-09-01 Brown, LM; Hanna, DT; Khaw, SL; Ekert, PG
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Hierarchy for targeting pro-survival BCL2 family proteins in multiple myeloma: pivotal role of MCL1 Blood - 2016-07-27 Gong, JN; Khong, T; Segal, D; Yao, Y; Riffkin, CD; GARNIER, JM; Khaw, SL; Lessene, G; Spencer, A; Herold, MJ; Roberts, AW; Huang, DC
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Venetoclax responses of pediatric ALL xenografts reveal MLLr ALL sensitivity, but overall requirement to target both BCL2 and BCLXL Blood - 2016-06-24 Khaw, SL; Suryani, S; Evans, K; Richmond, J; Robbins, A; Kurmasheva, RT; Billups, CA; Erickson, SW; Guo, Y; Houghton, PJ; Smith, MA; Carol, H; Roberts, AW; Huang, DC; Lock, RB
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BET inhibition represses miR17-92 to drive BIM-initiated apoptosis of normal and transformed hematopoietic cells Leukemia - 2016-03-08 Xu, Z; Sharp, PP; Yao, Y; Segal, D; Ang, CH; Khaw, SL; Aubrey, BJ; Gong, J; Kelly, GL; Herold, MJ; Strasser, A; Roberts, AW; Alexander, WS; Burns, CJ; Huang, DC; Glaser, SP
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The BIM deletion polymorphism: A paradigm of a permissive interaction between germline and acquired TKI resistance factors in chronic myeloid leukemia Oncotarget - 2015-10-28 Ko, TK; Chin, HS; Chuah, CT; Huang, JW; Ng, KP; Khaw, SL; Huang, DC; Ong, ST
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ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets NATURE MEDICINE - 2013-02 Souers, AJ; Leverson, JD; Boghaert, ER; Ackler, SL; Catron, ND; Chen, J; Dayton, BD; Ding, H; Enschede, SH; Fairbrother, WJ; Huang, DCS; Hymowitz, SG; Jin, S; Khaw, SL; Kovar, PJ; Lam, LT; Lee, J; Maecker, HL; Marsh, KC; Mason, KD; Mitten, MJ; Nimmer, PM; Oleksijew, A; Park, CH; Park, CM; Phillips, DC; Roberts, AW; Sampath, D; Seymour, JF; Smith, ML; Sullivan, GM; Tahir, SK; Tse, C; Wendt, MD; Xiao, Y; Xue, JC; Zhang, HC; Humerickhouse, RA; Rosenberg, SH; Elmore, SW
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Bcl-2, Bcl-x(L), and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells BLOOD - 2012-06-14 Merino, D; Khaw, SL; Glaser, SP; Anderson, DJ; Belmont, LD; Wong, CH; Yue, P; Robati, M; Phipson, B; Fairlie, WD; Lee, EF; Campbell, KJ; Vandenberg, CJ; Cory, S; Roberts, AW; Ludlam, MJC; Huang, DCS; Bouillet, P
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Substantial Susceptibility of Chronic Lymphocytic Leukemia to BCL2 Inhibition: Results of a Phase I Study of Navitoclax in Patients With Relapsed or Refractory Disease JOURNAL OF CLINICAL ONCOLOGY - 2012-02-10 Roberts, AW; Seymour, JF; Brown, JR; Wierda, WG; Kipps, TJ; Khaw, SL; Carney, DA; He, SZ; Huang, DCS; Xiong, H; Cui, Y; Busman, TA; McKeegan, EM; Krivoshik, AP; Enschede, SH; Humerickhouse, R
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Overcoming blocks in apoptosis with BH3-mimetic therapy in haematological malignancies PATHOLOGY - 2011-10 Khaw, SL; Huang, DCS; Roberts, AW
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The Bcl-2 Homology Domain 3 Mimetic ABT-737 Targets the Apoptotic Machinery in Acute Lymphoblastic Leukemia Resulting in Synergistic in Vitro and in Vivo Interactions with Established Drugs MOLECULAR PHARMACOLOGY - 2010-03 High, LM; Szymanska, B; Wilczynska-Kalak, U; Barber, N; O'Brien, R; Khaw, SL; Vikstrom, IB; Roberts, AW; Lock, RB
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Biomarkers and In Vivo Responses to the BH3 Mimetic, ABT-263, in Patients (pts) with Chronic Lymphocytic Leukemia (CLL) BLOOD - 2009-11-20 Khaw, SL; Huang, DC; He, S; Seymour, JF; Carney, D; Mason, KD; Chyla, B; Litvinovich, E; McKeegan, E; Krivoshik, A; Enschede, S; Humerickhouse, R; Roberts, AW
The BH3 mimetic compound, ABT-737, synergizes with a range of cytotoxic chemotherapy agents in chronic lymphocytic leukemia LEUKEMIA - 2009-11 Mason, KD; Khaw, SL; Rayeroux, KC; Chew, E; Lee, EF; Fairlie, WD; Grigg, AP; Seymour, JF; Szer, J; Huang, DCS; Roberts, AW
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BH3-mimetics - the solution to chemoresistance? LEUKEMIA & LYMPHOMA - 2009 Khaw, SL; Huang, DCS; Roberts, AW
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