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Showing results for: AUTHOR - Majewski, IJ

Found: 33 results

Finding a suitable library size to call variants in RNA-Seq BMC Bioinformatics - 2020-12-01 Quaglieri, A; Flensburg, C; Speed, TP; Majewski, IJ
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Chemotherapy and Venetoclax in Elderly Acute Myeloid Leukemia Trial (CAVEAT): A Phase Ib Dose-Escalation Study of Venetoclax Combined With Modified Intensive Chemotherapy J Clin Oncol - 2020-07-20 Chua, CC; Roberts, AW; Reynolds, J; Fong, CY; Ting, SB; Salmon, JM; Macraild, S; Ivey, A; Tiong, IS; Fleming, S; Brown, FC; Loo, S; Majewski, IJ; Bohlander, SK; Wei, AH
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A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction Nature Communications - 2020-06-19 Hildebrand, JM; Kauppi, M; Majewski, IJ; LIU, Z; Cox, AJ; Miyake, S; Petrie, EJ; Silk, MA; Li, Z; Tanzer, MC; Brumatti, G; Young, SN; Hall, C; Garnish, SE; Corbin, J; Stutz, MD; Di Rago, L; Gangatirkar, P; Josefsson, EC; Rigbye, K; Anderton, H; Rickard, JA; Tripaydonis, A; Sheridan, J; Scerri, TS; Jackson, VE; Czabotar, PE; Zhang, JG; Varghese, L; Allison, CC; Pellegrini, M; Tannahill, GM; Hatchell, EC; Willson, TA; Stockwell, D; de Graaf, CA; Collinge, J; Hilton, A; Silke, N; Spall, SK; Chau, D; Athanasopoulos, V; Metcalf, D; Laxer, RM; Bassuk, AG; Darbro, BW; Fiatarone Singh, MA; Vlahovich, N; Hughes, D; Kozlovskaia, M; Ascher, DB; Warnatz, K; Venhoff, N; Thiel, J; Biben, C; Blum, S; Reveille, J; Hildebrand, MS; Vinuesa, CG; McCombe, P; Brown, MA; Kile, BT; McLean, C; Bahlo, M; Masters, SL; Nakano, H; Ferguson, PJ; Murphy, JM; Alexander, WS; Silke, J
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The application of RNA sequencing for the diagnosis and genomic classification of pediatric acute lymphoblastic leukemia Blood Advances - 2020-03-10 Brown, LM; Lonsdale, A; Zhu, A; Davidson, NM; Schmidt, B; Hawkins, A; Wallach, E; Martin, M; Mechinaud, FM; Khaw, SL; Bartolo, RC; Ludlow, LEA; Challis, J; Brooks, I; Petrovic, V; Venn, NC; Sutton, R; Majewski, IJ; Oshlack, A; Ekert, PG
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SuperFreq: Integrated mutation detection and clonal tracking in cancer PLoS Computational Biology - 2020-02-13 Flensburg, C; Sargeant, T; Oshlack, A; Majewski, IJ
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Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML Blood - 2020-01-13 DiNardo, CD; Tiong, IS; Quaglieri, A; Macraild, S; Loghavi, S; Brown, FC; Thijssen, R; Pomilio, G; Ivey, A; Salmon, J; Glytsou, C; Fleming, SA; Zhang, Q; Ma, H; Patel, KP; Kornblau, SM; Xu, Z; Chua, CC; Chen, X; Blombery, P; Flensburg, C; Cummings, N; Aifantis, I; Kantarjian, H; Huang, DCS; Roberts, AW; Majewski, IJ; Konopleva, M; Wei, AH
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Targeted therapy and disease monitoring in CNTRL-FGFR1-driven leukaemia Pediatric Blood & Cancer - 2019-06-28 Brown, LM; Bartolo, RC; Davidson, NM; Schmidt, B; Brooks, I; Challis, J; Petrovic, V; Khuong-Quang, DA; MeChinaud, F; Khaw, SL; Majewski, IJ; Oshlack, A; Ekert, PG
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Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations Nature Communications - 2019-06-03 Birkinshaw, RW; Gong, JN; Luo, CS; Lio, D; White, CA; Anderson, MA; Blombery, P; Lessene, G; Majewski, IJ; Thijssen, R; Roberts, AW; Huang, DCS; Colman, PM; Czabotar, PE
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On fitness: how do mutations shape the biology of cancer? Biochemical Society Transactions - 2019-03-08 Majewski, IJ
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Acquisition of the recurrent Gly101Val mutation in BCL2 confers resistance to venetoclax in patients with progressive chronic lymphocytic leukemia Cancer Discovery - 2019-03 Blombery, P; Anderson, MA; Gong, JN; Thijssen, R; Birkinshaw, RW; Thompson, ER; Teh, CE; Nguyen, T; Xu, Z; Flensburg, C; Lew, TE; Majewski, IJ; Gray, DHD; Westerman, DA; Tam, CS; Seymour, JF; Czabotar, PE; Huang, DCS; Roberts, AW
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Clinker: visualising fusion genes detected in RNA-seq data Gigascience - 2018-07-04 Schmidt, BM; Davidson, NM; Hawkins, ADK; Bartolo, R; Majewski, IJ; Ekert, PG; Oshlack, A
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Integrative modeling identifies key determinants of inhibitor sensitivity in breast cancer cell lines Cancer Research - 2018-05 Jastrzebski, K; Thijssen, B; Kluin, RJ; de Lint, K; Majewski, IJ; Beijersbergen, RL; Wessels, LFA
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BAK/BAX-mediated apoptosis is a Myc-induced roadblock to reprogramming Stem Cell Reports - 2018-01-17 Kim, EJY; Anko, ML; Flensberg, C; Majewski, IJ; Geng, FS; Firas, J; Huang, DCS; van Delft, MF; Heath, JK
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MBD4 guards against methylation damage and germline deficiency predisposes to clonal hematopoiesis and early-onset AML Blood - 2018 Sanders, MA; Chew, E; Flensburg, C; Zeilemaker, A; Miller, SE; Al Hinai, AS; Bajel, A; Luiken, B; Rijken, M; McLennan, T; Hoogenboezem, RM; Kavelaars, FG; Frohling, S; Blewitt, ME; Bindels, EM; Alexander, WS; Lowenberg, B; Roberts, AW; Valk, PJM; Majewski, IJ
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The BRCA1ness signature is associated significantly with response to PARP inhibitor treatment versus control in the I-SPY 2 randomized neoadjuvant setting Breast Cancer Research - 2017-08-25 Severson, TM; Wolf, DM; Yau, C; Peeters, J; Wehkam, D; Schouten, PC; Chin, SF; Majewski, IJ; Michaut, M; Bosma, A; Pereira, B; Bismeijer, T; Wessels, L; Caldas, C; Bernards, R; Simon, IM; Glas, AM; Linn, S; van 't Veer, L
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A non-canonical function of Ezh2 preserves immune homeostasis EMBO Reports - 2017-02-21 Vasanthakumar, A; Xu, D; Lun, AT; Kueh, AJ; van Gisbergen, KP; Iannarella, N; Li, X; Yu, L; Wang, D; Williams, BR; Lee, SC; Majewski, IJ; Godfrey, DI; Smyth, GK; Alexander, WS; Herold, MJ; Kallies, A; Nutt, SL; Allan, RS
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Robust hyperparameter estimation protects against hypervariable genes and improves power to detect differential expression Ann Appl Stat - 2016-06 Phipson, B; Lee, S; Majewski, IJ; Alexander, WS; Smyth, GK
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The BCL2 selective inhibitor venetoclax induces rapid onset apoptosis of CLL cells in patients via a TP53 independent mechanism Blood - 2016-04-11 Anderson, MA; Deng, J; Seymour, JF; Tam, C; Kim, SY; Fein, J; Yu, L; Brown, JR; Westerman, D; Si, EG; Majewski, IJ; Segal, D; Heitner Enschede, SL; Huang, DC; Davids, MS; Letai, A; Roberts, AW
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Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis Blood - 2015-07-09 Lee, SC; Miller, S; Hyland, C; Kauppi, M; Lebois, M; Di Rago, L; Metcalf, D; Kinkel, SA; Josefsson, EC; Blewitt, ME; Majewski, IJ; Alexander, WS
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Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2 Blood - 2015-03-19 Kinkel, SA; Galeev, R; Flensburg, C; Keniry, A; Breslin, K; Gilan, O; Lee, S; Liu, J; Chen, K; Gearing, LJ; Moore, DL; Alexander, WS; Dawson, M; Majewski, IJ; Oshlack, A; Larsson, J; Blewitt, ME
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JAFFA: High sensitivity transcriptome-focused fusion gene detection Genome Med - 2015 Davidson, NM; Majewski, IJ; Oshlack, A
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Polycomb repressive complex 2 (PRC2) suppresses Emu-myc lymphoma Blood - 2013-10-10 Lee, SC; Phipson, B; Hyland, CD; Leong, HS; Allan, RS; Lun, A; Hilton, DJ; Nutt, SL; Blewitt, ME; Smyth, GK; Alexander, WS; Majewski, IJ
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The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism. Immunity - 2013-09-19 Murphy, JM; Czabotar, PE; Hildebrand, JM; Lucet, IS; Zhang, JG; Alvarez-Diaz, S; Lewis, R; Lalaoui, N; Metcalf, D; Webb, AI; Young, SN; Varghese, LN; Tannahill, GM; Hatchell, EC; Majewski, IJ; Okamoto, T; Dobson, RC; Hilton, DJ; Babon, JJ; Nicola, NA; Strasser, A; Silke, J; Alexander, WS
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Identification of recurrent FGFR3 fusion genes in lung cancer through kinome-centred RNA sequencing JOURNAL OF PATHOLOGY - 2013-07 Majewski, IJ; Mittempergher, L; Davidson, NM; Bosma, A; Willems, SM; Horlings, HM; de Rink, I; Greger, L; Hooijer, GKJ; Peters, D; Nederlof, PM; Hofland, I; de Jong, J; Wesseling, J; Kluin, RJC; Brugman, W; Kerkhoven, R; Nieboer, F; Roepman, P; Broeks, A; Muley, TR; Jassem, J; Niklinski, J; van Zandwijk, N; Brazma, A; Oshlack, A; van den Heuvel, M; Bernards, R
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An alpha-E-catenin (CTNNA1) mutation in hereditary diffuse gastric cancer JOURNAL OF PATHOLOGY - 2013-03 Majewski, IJ; Kluijt, I; Cats, A; Scerri, TS; de Jong, D; Kluin, RJC; Hansford, S; Hogervorst, FBL; Bosma, AJ; Hofland, I; Winter, M; Huntsman, D; Jonkers, J; Bahlo, M; Bernards, R
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