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Showing results for: AUTHOR - Samson, AL
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TDP-43 triggers mitochondrial DNA release via mPTP to activate cGAS/STING in ALS
Cell - 2020-10-03
Yu, CH; Davidson, S; Harapas, CR; Hilton, JB; Mlodzianoski, MJ; Laohamonthonkul, P; Louis, C; Low, RRJ; Moecking, J; De Nardo, D; Balka, KR; Calleja, DJ; Moghaddas, F; Ni, E; McLean, CA; Samson, AL; Tyebji, S; Tonkin, CJ; Bye, CR; Turner, BJ; Pepin, G; Gantier, MP; Rogers, KL; McArthur, K; Crouch, PJ; Masters, SL
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MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis
Nature Communications - 2020-06-19
Samson, AL; Zhang, Y; Geoghegan, ND; Gavin, XJ; Davies, KA; Mlodzianoski, MJ; Whitehead, LW; Frank, D; Garnish, SE; Fitzgibbon, C; Hempel, A; Young, SN; Jacobsen, AV; Cawthorne, W; Petrie, EJ; Faux, MC; Shield-Artin, K; Lalaoui, N; Hildebrand, JM; Silke, J; Rogers, KL; Lessene, G; Hawkins, ED; Murphy, JM
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Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies
Proceedings of the National Academy of Sciences of the United States of America - 2020-03-31
Petrie, EJ; Birkinshaw, RW; Koide, A; Denbaum, E; Hildebrand, JM; Garnish, SE; Davies, KA; Sandow, JJ; Samson, AL; Gavin, X; Fitzgibbon, C; Young, SN; Hennessy, PJ; Smith, PPC; Webb, AI; Czabotar, PE; Koide, S; Murphy, JM
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Viral MLKL homologs subvert necroptotic cell death by sequestering cellular RIPK3
Cell Reports - 2019-09-24
Petrie, EJ; Sandow, JJ; Lehmann, WIL; Liang, LY; Coursier, D; Young, SN; Kersten, WJA; Fitzgibbon, C; Samson, AL; Jacobsen, AV; Lowes, KN; Au, AE; Jousset Sabroux, H; Lalaoui, N; Webb, AI; Lessene, G; Manning, G; Lucet, IS; Murphy, JM
Link to Open Access at Publisher's Site
Necroptosis is dispensable for motor neuron degeneration in a mouse model of ALS
Cell Death and Differentiation - 2019-05
Wang, T; Perera, ND; Chiam, MDF; Cuic, B; Wanniarachchillage, N; Tomas, D; Samson, AL; Cawthorne, W; Valor, EN; Murphy, JM; Turner, BJ
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VDAC2 enables BAX to mediate apoptosis and limit tumor development
Nature Communications - 2018-11-26
Chin, HS; Li, MX; Tan, IKL; Ninnis, RL; Reljic, B; Scicluna, K; Dagley, LF; Sandow, JJ; Kelly, GL; Samson, AL; Chappaz, S; Khaw, SL; Chang, C; Morokoff, A; Brinkmann, K; Webb, A; Hockings, C; Hall, CM; Kueh, AJ; Ryan, MT; Kluck, RM; Bouillet, P; Herold, MJ; Gray, DHD; Huang, DCS; van Delft, MF; Dewson, G
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