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Showing results for: AUTHOR - Tonkin, CJ
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TDP-43 triggers mitochondrial DNA release via mPTP to activate cGAS/STING in ALS
Cell - 2020-10-03
Yu, CH; Davidson, S; Harapas, CR; Hilton, JB; Mlodzianoski, MJ; Laohamonthonkul, P; Louis, C; Low, RRJ; Moecking, J; De Nardo, D; Balka, KR; Calleja, DJ; Moghaddas, F; Ni, E; McLean, CA; Samson, AL; Tyebji, S; Tonkin, CJ; Bye, CR; Turner, BJ; Pepin, G; Gantier, MP; Rogers, KL; McArthur, K; Crouch, PJ; Masters, SL
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Catastrophic consequences: can the feline parasite Toxoplasma gondii prompt the purrfect neuroinflammatory storm following traumatic brain injury?
Journal of Neuroinflammation - 2020-07-25
Baker, TL; Sun, M; Semple, BD; Tyebji, S; Tonkin, CJ; Mychasiuk, R; Shultz, SR
Link to Open Access at Publisher's Site
Pathogenic infection in male mice changes sperm small RNA profiles and transgenerationally alters offspring behavior
Cell Reports - 2020-04-28
Tyebji, S; Hannan, AJ; Tonkin, CJ
Link to Open Access at Publisher's Site
Protein kinase a is essential for invasion of Plasmodium falciparum into human erythrocytes
MBio - 2019-10-08
Wilde, ML; Triglia, T; Marapana, D; Thompson, JK; Kouzmitchev, AA; Bullen, HE; Gilson, PR; Cowman, AF; Tonkin, CJ
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Impaired social behaviour and molecular mediators of associated neural circuits during chronic Toxoplasma gondii infection in female mice
Brain Behaviour and Immunity - 2019-08
Tyebji, S; Seizova, S; Garnham, AL; Hannan, AJ; Tonkin, CJ
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An apically located hybrid guanylate cyclase-ATPase is critical for the initiation of Ca(2+) signalling and motility in Toxoplasma gondii
Journal of Biological Chemistry - 2019-07
Yang, L; Uboldi, AD; Seizova, S; Wilde, ML; Coffey, MJ; Katris, NJ; Yamaryo-Botte, Y; Kocan, M; Bathgate, RAD; Stewart, RJ; McConville, MJ; Thompson, PE; Botte, CY; Tonkin, CJ
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Characterization of the ATP4 ion pump in Toxoplasma gondii
Journal of Biological Chemistry - 2019-02-05
Lehane, AM; Dennis, ASM; Bray, KO; Li, D; Rajendran, E; Mccoy, JM; McArthur, HM; Winterberg, M; Rahimi, F; Tonkin, CJ; Kirk, K; van Dooren, GG
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Evaluation of 4-amino 2-anilinoquinazolines against Plasmodium and other apicomplexan parasites in vitro and in a P. falciparum humanized NOD-scid IL2Rgamma(null) mouse model of malaria
Antimicrobial Agents and Chemotherapy - 2019-02
Gilson, PR; Nguyen, W; Poole, WA; Teixeira, JE; Thompson, JK; Guo, K; Stewart, RJ; Ashton, TD; White, KL; Sanz, LM; Gamo, FJ; Charman, SA; Wittlin, S; Duffy, J; Tonkin, CJ; Tham, WH; Crabb, BS; Cooke, BM; Huston, CD; Cowman, AF; Sleebs, BE
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Structure of Plasmodium falciparum Rh5-CyRPA-Ripr invasion complex
Nature - 2019-01
Wong, W; Huang, R; Menant, S; Hong, C; Sandow, JJ; Birkinshaw, RW; Healer, J; Hodder, AN; Kanjee, U; Tonkin, CJ; Heckmann, D; Soroka, V; Sogaard, TMM; Jorgensen, T; Duraisingh, MT; Czabotar, PE; de Jongh, WA; Tham, WH; Webb, AI; Yu, Z; Cowman, AF
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Protein O-fucosyltransferase 2-mediated O-glycosylation of the adhesin MIC2 is dispensable for Toxoplasma gondii tachyzoite infection
Journal of Biological Chemistry - 2018-12-04
Khurana, S; Coffey, MJ; John, A; Uboldi, AD; Huynh, MH; Stewart, RJ; Carruthers, V; Tonkin, CJ; Goddard-Borger, ED; Scott, NE
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Toxoplasmosis: A pathway to neuropsychiatric disorders
Neuroscience and Biobehavioral Reviews - 2018-11-23
Tyebji, S; Seizova, S; Hannan, AJ; Tonkin, CJ
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Aspartyl protease 5 matures dense granule proteins that reside at the host-parasite interface in Toxoplasma gondii
MBio - 2018-10-30
Coffey, MJ; Dagley, LF; Seizova, S; Kapp, EA; Infusini, G; Roos, DS; Boddey, JA; Webb, AI; Tonkin, CJ
Link to Open Access at Publisher's Site
Protein kinase A negatively regulates Ca2+ signalling in Toxoplasma gondii
PLoS Biology - 2018-09-12
Uboldi, AD; Wilde, ML; McRae, EA; Stewart, RJ; Dagley, LF; Yang, L; Katris, NJ; Hapuarachchi, SV; Coffey, MJ; Lehane, AM; Botte, CY; Waller, RF; Webb, AI; McConville, MJ; Tonkin, CJ
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Elucidating the mitochondrial proteome of Toxoplasma gondii reveals the presence of a divergent cytochrome c oxidase
eLife - 2018-09-11
Seidi, A; Muellner-Wong, LS; Rajendran, E; Tjhin, ET; Dagley, L; Aw, VY; Faou, P; Webb, AI; Tonkin, CJ; van Dooren, GG
Link to Open Access at Publisher's Site
Plasmodium falciparum subtilisin-like ookinete protein SOPT plays an important and conserved role during ookinete infection of the Anopheles stephensi midgut
Molecular Microbiology - 2018-08
Armistead, JS; Jennison, C; O'Neill, MT; Lopaticki, S; Liehl, P; Hanson, KK; Annoura, T; Rajasekaran, P; Erickson, SM; Tonkin, CJ; Khan, SM; Mota, MM; Boddey, JA
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MYR1-dependent effectors are the major drivers of a host cell's early response to Toxoplasma, including counteracting MYR1-independent effects
MBio - 2018-04-03
Naor, A; Panas, MW; Marino, N; Coffey, MJ; Tonkin, CJ; Boothroyd, JC
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Development of a Novel CD4+ TCR Transgenic Line That Reveals a Dominant Role for CD8+ Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria
Journal of Immunology - 2017-10-30
Fernandez-Ruiz, D; Lau, LS; Ghazanfari, N; Jones, CM; Ng, WY; Davey, GM; Berthold, D; Holz, L; Kato, Y; Enders, MH; Bayarsaikhan, G; Hendriks, SH; Lansink, LIM; Engel, JA; Soon, MSF; James, KR; Cozijnsen, A; Mollard, V; Uboldi, AD; Tonkin, CJ; de Koning-Ward, TF; Gilson, PR; Kaisho, T; Haque, A; Crabb, BS; Carbone, FR; McFadden, GI; Heath, WR
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Analysis of Ca2+ mediated signaling regulating Toxoplasma infectivity reveals complex relationships between key molecules
Cellular Microbiology - 2017-10-26
Stewart, RJ; Whitehead, L; Nijagal, B; Sleebs, BE; Lessene, G; McConville, MJ; Rogers, KL; Tonkin, CJ
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The molecular basis of erythrocyte invasion by malaria parasites
Cell Host Microbe - 2017-08-09
Cowman, AF; Tonkin, CJ; Tham, WH; Duraisingh, MT
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A forward-genetic screen identifies a negative regulator of rapid Ca2+-dependent cell egress in the intracellular parasite Toxoplasma gondii
Journal of Biological Chemistry - 2017-03-03
Mccoy, JM; Stewart, RJ; Uboldi, AD; Li, D; Schroder, J; Scott, NE; Papenfuss, AT; Lehane, AM; Foster, LJ; Tonkin, CJ
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Truncated latrunculins as actin inhibitors targeting Plasmodium falciparum motility and host cell invasion
J Med Chem - 2016-12-22
Johnson, S; Rahmani, R; Drew, DR; Williams, MJ; Wilkinson, M; Tan, YH; Huang, JX; Tonkin, CJ; Beeson, JG; Baum, J; Smith, BJ; Baell, JB
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Role of the ER and Golgi in protein export by Apicomplexa
Curr Opin Cell Biol - 2016-03-25
Coffey, MJ; Jennison, C; Tonkin, CJ; Boddey, JA
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An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell
Elife - 2015-11-18
Coffey, MJ; Sleebs, BE; Uboldi, AD; Garnham, AL; Franco, M; Marino, ND; Panas, MW; Ferguson, DJ; Enciso, M; O'Neill, MT; Lopaticki, S; Stewart, RJ; Dewson, G; Smyth, GK; Smith, BJ; Masters, SL; Boothroyd, JC; Boddey, JA; Tonkin, CJ
Link to Open Access at Publisher's Site
Disassembly activities of actin depolymerization factor (ADF) is associated with distinct cellular processes in apicomplexan parasites
Mol Biol Cell - 2015-07-08
Haase, S; Zimmermann, D; Olshina, MA; Wilkinson, M; Fisher, F; Tan, YH; Stewart, RJ; Tonkin, CJ; Wong, W; Kovar, DR; Baum, J
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Rhomboid proteases in invasion and replication of Apicomplexa
Mol Microbiol - 2015-07
Stewart, RJ; Tonkin, CJ
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