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Showing results for: AUTHOR - Webb, AI
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Cytotoxic T Cells swarm by homotypic chemokine signalling
Elife - 2020-10-13
Galeano Nino, JL; Pageon, SV; Tay, SS; Colakoglu, F; Kempe, D; Hywood, J; Mazalo, JK; Cremasco, J; Govendir, MA; Dagley, LF; Hsu, K; Rizzetto, S; Zieba, J; Rice, G; Prior, V; O'Neill, GM; Williams, RJ; Nisbet, DR; Kramer, B; Webb, AI; Luciani, F; Read, MN; Biro, M
Link to Open Access at Publisher's Site
A regulatory region on RIPK2 is required for XIAP binding and NOD signaling activity
EMBO Reports - 2020-09-21
Heim, VJ; Dagley, LF; Stafford, CA; Hansen, FM; Clayer, E; Bankovacki, A; Webb, AI; Lucet, IS; Silke, J; Nachbur, U
Link to Publisher's Version
BAK core dimers bind lipids and can be bridged by them
Nature Structural & Molecular Biology - 2020-09-14
Cowan, AD; Smith, NA; Sandow, JJ; Kapp, EA; Rustam, YH; Murphy, JM; Brouwer, JM; Bernardini, JP; Roy, MJ; Wardak, AZ; Tan, IK; Webb, AI; Gulbis, JM; Smith, BJ; Reid, GE; Dewson, G; Colman, PM; Czabotar, PE
Link to Publisher's Version
Phosphorylation by Aurora B kinase regulates caspase-2 activity and function
Cell Death and Differentiation - 2020-08-18
Lim, Y; De Bellis, D; Sandow, JJ; Capalbo, L; D'Avino, PP; Murphy, JM; Webb, AI; Dorstyn, L; Kumar, S
Link to Open Access at Publisher's Site
How IGF-II binds to the human type 1 insulin-like growth factor receptor
Structure - 2020-05-26
Xu, Y; Kirk, NS; Venugopal, H; Margetts, MB; Croll, TI; Sandow, JJ; Webb, AI; Delaine, CA; Forbes, BE; Lawrence, MC
Link to Open Access at Publisher's Site
ROCK-mediated selective activation of PERK signalling causes fibroblast reprogramming and tumour progression through a CRELD2-dependent mechanism
Nature Cell Biology - 2020-05-25
Boyle, ST; Poltavets, V; Kular, J; Pyne, NT; Sandow, JJ; Lewis, AC; Murphy, KJ; Kolesnikoff, N; Moretti, PAB; Tea, MN; Tergaonkar, V; Timpson, P; Pitson, SM; Webb, AI; Whitfield, RJ; Lopez, AF; Kochetkova, M; Samuel, MS
Link to Publisher's Version
Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies
Proceedings of the National Academy of Sciences of the United States of America - 2020-03-31
Petrie, EJ; Birkinshaw, RW; Koide, A; Denbaum, E; Hildebrand, JM; Garnish, SE; Davies, KA; Sandow, JJ; Samson, AL; Gavin, X; Fitzgibbon, C; Young, SN; Hennessy, PJ; Smith, PPC; Webb, AI; Czabotar, PE; Koide, S; Murphy, JM
Link to Publisher's Version
A class of gammadelta T cell receptors recognize the underside of the antigen-presenting molecule MR1
Science - 2019-12-20
Le Nours, J; Gherardin, NA; Ramarathinam, SH; Awad, W; Wiede, F; Gully, BS; Khandokar, Y; Praveena, T; Wubben, JM; Sandow, JJ; Webb, AI; von Borstel, A; Rice, MT; Redmond, SJ; Seneviratna, R; Sandoval-Romero, ML; Li, S; Souter, MNT; Eckle, SBG; Corbett, AJ; Reid, HH; Liu, L; Fairlie, DP; Giles, EM; Westall, GP; Tothill, RW; Davey, MS; Berry, R; Tiganis, T; McCluskey, J; Pellicci, DG; Purcell, AW; Uldrich, AP; Godfrey, DI; Rossjohn, J
Link to Publisher's Version
A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis
Nature Chemical Biology - 2019-11
van Delft, MF; Chappaz, S; Khakham, Y; Bui, CT; Debrincat, MA; Lowes, KN; Brouwer, JM; Grohmann, C; Sharp, PP; Dagley, LF; Li, L; McArthur, K; Luo, MX; Chin, HS; Fairlie, WD; Lee, EF; Segal, D; Duflocq, S; Lessene, R; Bernard, S; Peilleron, L; Nguyen, T; Miles, C; Wan, SS; Lane, RM; Wardak, A; Lackovic, K; Colman, PM; Sandow, JJ; Webb, AI; Czabotar, PE; Dewson, G; Watson, KG; Huang, DCS; Lessene, G; Kile, BT
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Generation of novel Id2 and E2-2, E2A and HEB antibodies reveals novel Id2 binding partners and species-specific expression of E-proteins in NK cells
Molecular Immunology - 2019-11
Rautela, J; Dagley, LF; Kratina, T; Anthony, A; Goh, W; Surgenor, E; Delconte, RB; Webb, AI; ELWOOD, N; Groom, JR; Souza-Fonseca-Guimaraes, F; Corcoran, L; Huntington, ND
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Kelch-like protein 5-mediated ubiquitination of lysine 183 promotes proteasomal degradation of sphingosine kinase 1
Biochemical Journal - 2019-10-14
Powell, JA; Pitman, MR; Zebol, JR; Moretti, PA; Neubauer, HA; Davies, LT; Lewis, AC; Dagley, LF; Webb, AI; Costabile, M; Pitson, SM
Link to Publisher's Version
RIPLET and not TRIM25 is required for endogenous RIG-I-dependent anti-viral responses
Immunology and Cell Biology - 2019-10
Hayman, TJ; Hsu, AC; Kolesnik, TB; Dagley, LF; Willemsen, J; Tate, MD; Baker, PJ; Kershaw, NJ; Kedzierski, L; Webb, AI; Wark, PA; Kedzierska, K; Masters, SL; Belz, GT; Binder, M; Hansbro, PM; Nicola, NA; Nicholson, SE
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Viral MLKL homologs subvert necroptotic cell death by sequestering cellular RIPK3
Cell Reports - 2019-09-24
Petrie, EJ; Sandow, JJ; Lehmann, WIL; Liang, LY; Coursier, D; Young, SN; Kersten, WJA; Fitzgibbon, C; Samson, AL; Jacobsen, AV; Lowes, KN; Au, AE; Jousset Sabroux, H; Lalaoui, N; Webb, AI; Lessene, G; Manning, G; Lucet, IS; Murphy, JM
Link to Open Access at Publisher's Site
Therapeutic blockade of activin-A improves NK cell function and antitumor immunity
Science Signaling - 2019-08-27
Rautela, J; Dagley, LF; de Oliveira, CC; Schuster, IS; Hediyeh-Zadeh, S; Delconte, RB; Cursons, J; Hennessy, R; Hutchinson, DS; Harrison, C; Kita, B; Vivier, E; Webb, AI; Degli-Esposti, MA; Davis, MJ; Huntington, ND; Souza-Fonseca-Guimaraes, F
Link to Publisher's Version
Loss of Bcl-G, a Bcl-2 family member, augments the development of inflammation-associated colorectal cancer
Cell Death and Differentiation - 2019-07-11
Nguyen, PM; Dagley, LF; Preaudet, A; Lam, N; Giam, M; Fung, KY; Aizel, K; van Duijneveldt, G; Tan, CW; Hirokawa, Y; Yip, HYK; Love, CG; Poh, AR; Cruz, A; Burstroem, C; Feltham, R; Abdirahman, SM; Meiselbach, K; Low, RRJ; Palmieri, M; Ernst, M; Webb, AI; BURGESS, T; Sieber, OM; Bouillet, P; Putoczki, TL
Link to Open Access at Publisher's Site
Universal solid-phase protein preparation (USP(3)) for bottom-up and top-down proteomics
Journal of Proteome Research - 2019-07-05
Dagley, LF; Infusini, G; Larsen, RH; Sandow, JJ; Webb, AI
Link to Publisher's Version
BAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial Association
Cell Reports - 2019-04-09
Dengler, MA; Robin, AY; Gibson, L; Li, MX; Sandow, JJ; Iyer, S; Webb, AI; Westphal, D; Dewson, G; Adams, JM
Link to Open Access at Publisher's Site
Structure of Plasmodium falciparum Rh5-CyRPA-Ripr invasion complex
Nature - 2019-01
Wong, W; Huang, R; Menant, S; Hong, C; Sandow, JJ; Birkinshaw, RW; Healer, J; Hodder, AN; Kanjee, U; Tonkin, CJ; Heckmann, D; Soroka, V; Sogaard, TMM; Jorgensen, T; Duraisingh, MT; Czabotar, PE; de Jongh, WA; Tham, WH; Webb, AI; Yu, Z; Cowman, AF
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Aspartyl protease 5 matures dense granule proteins that reside at the host-parasite interface in Toxoplasma gondii
MBio - 2018-10-30
Coffey, MJ; Dagley, LF; Seizova, S; Kapp, EA; Infusini, G; Roos, DS; Boddey, JA; Webb, AI; Tonkin, CJ
Link to Open Access at Publisher's Site
Ensemble properties of bax determine its function
Structure - 2018-10
Robin, AY; Iyer, S; Birkinshaw, RW; Sandow, J; Wardak, A; Luo, CS; Shi, M; Webb, AI; Czabotar, PE; Kluck, RM; Colman, PM
Link to Publisher's Version
Protein kinase A negatively regulates Ca2+ signalling in Toxoplasma gondii
PLoS Biology - 2018-09-12
Uboldi, AD; Wilde, ML; McRae, EA; Stewart, RJ; Dagley, LF; Yang, L; Katris, NJ; Hapuarachchi, SV; Coffey, MJ; Lehane, AM; Botte, CY; Waller, RF; Webb, AI; McConville, MJ; Tonkin, CJ
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Elucidating the mitochondrial proteome of Toxoplasma gondii reveals the presence of a divergent cytochrome c oxidase
eLife - 2018-09-11
Seidi, A; Muellner-Wong, LS; Rajendran, E; Tjhin, ET; Dagley, L; Aw, VY; Faou, P; Webb, AI; Tonkin, CJ; van Dooren, GG
Link to Open Access at Publisher's Site
Plasma membrane profiling during enterohemorrhagic E. coli infection reveals that the metalloprotease StcE cleaves CD55 from host epithelial surfaces
Journal of Biological Chemistry - 2018-09-06
Furniss, RCD; Low, WW; Mavridou, DAI; Dagley, LF; Webb, AI; Tate, E; Clements, A
Link to Publisher's Version
Plasmepsin V cleaves malaria effector proteins in a distinct endoplasmic reticulum translocation interactome for export to the erythrocyte
Nature Microbiology - 2018-09
Marapana, DS; Dagley, LF; Sandow, JJ; Nebl, T; Triglia, T; Pasternak, M; Dickerman, BK; Crabb, BS; Gilson, PR; Webb, AI; Boddey, JA; Cowman, AF
Link to Publisher's Version
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis
Nature Communications - 2018-06-21
Petrie, EJ; Sandow, JJ; Jacobsen, AV; Smith, BJ; Griffin, MDW; Lucet, IS; Dai, W; Young, SN; Tanzer, MC; Wardak, A; Liang, LY; Cowan, AD; Hildebrand, JM; Kersten, WJA; Lessene, G; Silke, J; Czabotar, PE; Webb, AI; Murphy, JM
Link to Open Access at Publisher's Site
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