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11562
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The role of LNK (SH2B3) in the regulation of JAK-STAT signalling in haematopoiesis
Pharmaceuticals - 2022-12-24
Morris, R; Butler, L; PERKINS, A; Kershaw, NJ; Babon, JJ
Abstract
Non-genetic determinants of malignant clonal fitness at single-cell resolution
Nature - 2022-12-08
Fennell, KA; Vassiliadis, D; Lam, EYN; Martelotto, LG; Balic, JJ; Hollizeck, S; Weber, TS; Semple, T; Wang, Q; Miles, DC; MacPherson, L; Chan, YC; Guirguis, AA; Kats, LM; Wong, ES; Dawson, SJ; Naik, SH; Dawson, MA
Abstract
Identifying targets of protective antibodies against severe malaria in Papua, Indonesia using locally expressed domains of Plasmodium falciparum Erythrocyte Membrane Protein 1
Infection and Immunity - 2022-12-06
Rambhatla, JS; Tonkin-Hill, GQ; Takashima, E; Tsuboi, T; Noviyanti, R; Trianty, L; Sebayang, BF; Lampah, DA; Marfurt, J; Price, RN; Anstey, NM; Papenfuss, AT; Damelang, T; Chung, AW; Duffy, MF; Rogerson, SJ
Abstract
CyTOF mass cytometry analysis of human memory CD4(+) T cells and memory B cells
STAR Protocols - 2022-06-17
Ioannidis, LJ; Mitchell, AJ; Zheng, T; Hansen, DS
Abstract
Long-term control of melanoma adrenal metastasis treated with radiotherapy
Melanoma Research - 2022-06-01
McCann, B; Higgins, M; Kok, DL; Hong, W; Alipour, R; Chua, MST
Abstract
Tankyrase-mediated ADP-ribosylation is a regulator of TNF-induced death
Science Advances - 2022-05-13
Liu, L; Sandow, JJ; Leslie Pedrioli, DM; Samson, AL; Silke, N; Kratina, T; Ambrose, RL; Doerflinger, M; Hu, Z; Morrish, E; Chau, D; Kueh, AJ; Fitzibbon, C; Pellegrini, M; Pearson, JS; Hottiger, MO; Webb, AI; Lalaoui, N; Silke, J
Abstract
Enhancing our chances of picking a winner in higher-risk myelodysplastic syndromes
British Journal of Haematology - 2022-05-11
Wei, AH; Seymour, JF
Abstract
Malaria transmission structure in the Peruvian Amazon through antibody signatures to Plasmodium vivax
PLOS Neglected Tropical DIseases - 2022-05-09
Rosado, J; Carrasco-Escobar, G; Nolasco, O; Garro, K; Rodriguez-Ferruci, H; Guzman-Guzman, M; Llanos-Cuentas, A; Vinetz, JM; Nekkab, N; White, MT; Mueller, I; Gamboa, D
Abstract
Zbtb20 identifies and controls a thymus-derived population of regulatory T cells that play a role in intestinal homeostasis
Science Immunology - 2022-05-06
Krzyzanowska, AK; Haynes Ii, RAH; Kovalovsky, D; Lin, HC; Osorio, L; Edelblum, KL; Corcoran, LM; Rabson, AB; Denzin, LK; Sant'Angelo, DB
Abstract
Nickel-Catalyzed C-N Cross-Coupling of 4-Chloro-1,8-naphthalimides and Bulky, Primary Alkylamines at Room Temperature
Journal of Organic Chemistry - 2022
Tassone, JP; Lundrigan, T; Ashton, TD; Stradiotto, M
Abstract
Death by differentiation: CD4(+) T cells kick out suspicious stem cells
Cell Stem Cell - 2022-05-05
Tomei, S; Audiger, C; Naik, SH
Abstract
Treatment-free remission after ceasing venetoclax-based therapy in patients with acute myeloid leukemia
Blood Advances - 2022-05-05
Chua, CC; Hammond, D; Kent, A; Tiong, IS; Konopleva, MY; Pollyea, DA; DiNardo, CD; Wei, AH
Abstract
Editorial on the special issue on Plasmodium vivax: Current situation and challenges towards elimination
Parasitology International - 2022-05-05
Tsuboi, T; del Portillo, HA; Mueller, I
Lynch syndrome testing of colorectal cancer patients in a high-income country with universal healthcare: a retrospective study of current practice and gaps in seven Australian hospitals
Hereditary Cancer in Clinical Practice - 2022-05-04
Steinberg, J; Chan, P; Hogden, E; Tiernan, G; Morrow, A; Kang, YJ; He, E; Venchiarutti, R; Titterton, L; Sankey, L; Pearn, A; Nichols, C; McKay, S; Hayward, A; Egoroff, N; Engel, A; Gibbs, P; Goodwin, A; Harris, M; Kench, JG; Pachter, N; Parkinson, B; Pockney, P; Ragunathan, A; SMYTH, C; Solomon, M; Steffens, D; Toh, JWT; Wallace, M; Canfell, K; Gill, A; Macrae, F; Tucker, K; Taylor, N
Abstract
De novo-designed transmembrane domains tune engineered receptor functions
Elife - 2022-05-04
Elazar, A; Chandler, NJ; Davey, AS; Weinstein, JY; Nguyen, JV; Trenker, R; Cross, RS; Jenkins, MR; Call, MJ; Call, ME; Fleishman, SJ
Abstract
Real-world first-line systemic therapy patterns in metastatic castration-resistant prostate cancer
BJUI Compass - 2022-05
Anton, A; Pillai, S; Semira, MC; Wong, S; Shapiro, J; Weickhardt, A; Azad, A; Kwan, EM; Spain, L; Gunjur, A; Torres, J; Parente, P; Parnis, F; Goh, J; Baenziger, O; Gibbs, P; Tran, B
Abstract
Endovascular Thrombectomy Versus Medical Management in Isolated M2 Occlusions: Pooled Patient-Level Analysis from the EXTEND-IA Trials, INSPIRE, and SELECT Studies
Annals of Neurology - 2022-05
Sarraj, A; Parsons, M; Bivard, A; Hassan, AE; Abraham, MG; Wu, T; Kleinig, T; Lin, L; Chen, C; Levi, C; Dong, Q; Cheng, X; Butcher, KS; Choi, P; Yassi, N; Shah, D; Sharma, G; Pujara, D; Shaker, F; Blackburn, S; Dewey, H; Thijs, V; Sitton, CW; Donnan, GA; Mitchell, PJ; Yan, B; Grotta, JG; Albers, GW; Davis, SM; Campbell, B; Select Investigators,; the Extend- IAInvestigators,; the Extend- IATNKInvestigators,; the Extend- IATNKPart II Investigators,; the Inspire Study Group,
Abstract
BRCA mutations lead to XIAP overexpression and sensitise ovarian cancer to inhibitor of apoptosis (IAP) family inhibitors
British Journal of Cancer - 2022-04-30
Cremona, M; Vandenberg, CJ; Farrelly, AM; Madden, SF; Morgan, C; Kalachand, R; McAlpine, JN; Toomey, S; Huntsman, DG; Grogan, L; Breathnach, O; MORRIS, P; Carey, MS; Scott, CL; Hennessy, BT
Abstract
Comparison of tenecteplase with alteplase for the early treatment of ischaemic stroke in the Melbourne Mobile Stroke Unit (TASTE-A): a phase 2, randomised, open-label trial
Lancet Neurology - 2022-04-29
Bivard, A; Zhao, H; Churilov, L; Campbell, BCV; Coote, S; Yassi, N; Yan, B; Valente, M; Sharobeam, A; Balabanski, AH; Dos Santos, A; Ng, JL; Yogendrakumar, V; Ng, F; Langenberg, F; Easton, D; Warwick, A; Mackey, E; MacDonald, A; Sharma, G; Stephenson, M; Smith, K; Anderson, D; Choi, P; Thijs, V; Ma, H; Cloud, GC; Wijeratne, T; Olenko, L; Italiano, D; Davis, SM; Donnan, GA; Parsons, MW
Abstract
Tenecteplase versus Alteplase for Stroke Thrombolysis Evaluation Trial in the Ambulance (Mobile Stroke Unit-TASTE-A): protocol for a prospective randomised, open-label, blinded endpoint, phase II superiority trial of tenecteplase versus alteplase for ischaemic stroke patients presenting within 4.5 hours of symptom onset to the mobile stroke unit
BMJ Open - 2022-04-29
Bivard, A; Zhao, H; Coote, S; Campbell, B; Churilov, L; Yassi, N; Yan, B; Valente, M; Sharobeam, A; Balabanski, A; Dos Santos, A; Ng, F; Langenberg, F; Stephenson, M; Smith, K; Bernard, S; Thijs, V; Cloud, G; Choi, P; Ma, H; Wijeratne, T; Chen, C; Olenko, L; Davis, SM; Donnan, GA; Parsons, M
Abstract
Deletion of Grin1 in mouse megakaryocytes reveals NMDA receptor role in platelet function and proplatelet formation
Blood - 2022-04-28
Hearn, JI; Green, TN; Hisey, CL; Bender, M; Josefsson, EC; Knowlton, N; Baumann, J; Poulsen, RC; Bohlander, SK; Kalev-Zylinska, ML
Abstract
Is increasing nodal count associated with improved recurrence-free and overall survival following standard right hemicolectomy for cancer?
Journal of Surgical Oncology - 2022-04-28
Hayes, IP; Milanzi, E; Gibbs, P; Faragher, I; Reece, JC
Abstract
Deficiency in coatomer complex I causes aberrant activation of STING signalling
Nature Communications - 2022-04-28
Steiner, A; Hrovat-Schaale, K; Prigione, I; Yu, CH; Laohamonthonkul, P; Harapas, CR; Low, RRJ; De Nardo, D; Dagley, LF; Mlodzianoski, MJ; Rogers, KL; Zillinger, T; Hartmann, G; Gantier, MP; Gattorno, M; Geyer, M; Volpi, S; Davidson, S; Masters, SL
Abstract
TLR7 gain-of-function genetic variation causes human lupus
Nature - 2022-04-27
Brown, GJ; Cañete, PF; Wang, H; Medhavy, A; Bones, J; Roco, JA; He, Y; Qin, Y; Cappello, J; Ellyard, JI; Bassett, K; Shen, Q; Burgio, G; Zhang, Y; Turnbull, C; Meng, X; Wu, P; Cho, E; Miosge, LA; Andrews, TD; Field, MA; Tvorogov, D; Lopez, AF; Babon, JJ; López, CA; Gónzalez-Murillo, Á; Garulo, DC; Pascual, V; Levy, T; Mallack, EJ; Calame, DG; Lotze, T; Lupski, JR; Ding, H; Ullah, TR; Walters, GD; Koina, ME; Cook, MC; Shen, N; de Lucas Collantes, C; Corry, B; Gantier, MP; Athanasopoulos, V; Vinuesa, CG
Abstract
Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer
Cell Metabolism - 2022-04-23
Best, SA; Gubser, PM; Sethumadhavan, S; Kersbergen, A; Negrón Abril, YL; Goldford, J; Sellers, K; Abeysekera, W; Garnham, AL; McDonald, JA; Weeden, CE; Anderson, D; Pirman, D; Roddy, TP; Creek, DJ; Kallies, A; Kingsbury, G; Sutherland, KD
Abstract
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